2′,6′-DiMethylcarbonylphenyl-10-sulfopropylacridiniumM-9-carboxylate 4′-NHS Ester CAS:194357-64-7

I-2',6'-DiMethylcarbonylphenyl-10-sulfopropylacridinium-9-carboxylate 4'-NHS ester yikhemikhali yekhemikhali kunye nesakhiwo esiyinkimbinkimbi se-molecular.Iqulethe iqela le-sulfopropylacridinium kunye neqela elisebenzayo le-carboxylate ester.Ubukho be-ester moiety bubonisa ukuba i-reactive kwaye ingasetyenziselwa njengeleyibhile okanye i-agent yokuguqula i-biomolecules.

Iqela le-compound ye-sulfopropylacridinium licebisa ukuba inokuba nezicelo ezinokuthi zisetyenziswe kwiimvavanyo ezisekelwe kwi-fluorescence, apho inokuthi isetyenziswe njengeprobe ye-fluorescent okanye idayi yokukhangela kunye nokuhlalutya i-biomolecules.Isenokuba nokubaluleka kwizifundo zeenkqubo zeselula, ezifana ne-intracellular calcium signaling.

Ukufakwa kweqela le-ester le-NHS libonisa ukuba linokusabela ngee-amine eziphambili, ezifana nezo zifunyenwe kwiiprotheni okanye i-peptides, ukwenza iibhondi ze-amide ezizinzile.Oku kuphinda kusebenze kwenza kube luncedo kwizicelo ze-bioconjugation, apho ingasetyenziselwa ukubhala okanye ukuguqula i-biomolecules kunye nezinye iiamolekyu ezisebenzayo, ezifana ne-fluorophores okanye iithegi.

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Iinkcukacha zeMveliso

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Isicelo kunye nesiphumo

Ngokuqhelekileyo, iikhompawundi eziqulethe i-acridinium derivatives kunye namaqela asebenzayo e-NHS ester anokuba nezicelo ezahlukeneyo, ngokukodwa kwintsimi ye-bioconjugation kunye ne-labeling ye-fluorescence.Ngokuqhelekileyo zisetyenziselwa ukubhala ii-biomolecules, ezifana neeprotheni, iipeptides, kunye ne-nucleic acids, kunye ne-fluorescent okanye amanye amaqela asebenzayo.

Iqela le-ester le-NHS livumela ukuba kukhethwe ukudibanisa okukhethiweyo kunye nee-amine eziphambili, ezifumaneka ngokuqhelekileyo kwii-biomolecules.Oku kwenza ukuba uncamathiselo lwedayi ye-fluorescent kwi-molekyuli ekujoliswe kuyo, ivumela ukubonwa okanye ukufunyanwa kwizicelo ezahlukeneyo zebhayoloji ezifana ne-fluorescence microscopy, i-cytometry yokuhamba, okanye i-enzyme-linked immunosorbent assays (ELISA).

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Iinkcukacha ezongezelelweyo:

Ukuqamba	I-C30H26N2O9S
Isivavanyi	99%
Imbonakalo	Umgubo omhlophe
Inombolo yeCAS.	194357-64-7
Ukupakisha	Incinci kwaye ininzi
Beka ubomi kwishelufa	iminyaka eyi-2
Ugcino	Gcina kwindawo epholileyo neyomileyo
Isiqinisekiso	ISO.