2′-(4-METHYLUMBELLIFERYL)-ALPHA-DN-ACETYLNEURAMINIC ACID SODIUM SALT CAS:76204-02-9 Umfanekiso okhoyo

2′-(4-METHYLUMBELLIFERYL)-ALPHA-DN-ACETYLNEURAMINIC ACID SODIUM ISAT CAS:76204-02-9

I-2'- (4-Methylumbelliferyl) -alpha-DN-acetylneuraminic ityuwa ye-sodium ityuwa yikhemikhali esetyenziswa ngokuqhelekileyo kwiimvavanyo zokuxilonga kunye nophando.Yinto ephuma kwi-fluorescent ebhalwe nge-sialic acid, udidi lwemolekyuli yecarbohydrate efumaneka kumphezulu weeseli.

Le khompawundi isetyenziswa njenge-substrate yee-enzymes ezibizwa ngokuba yi-neuraminidases, esebenza ukususa iintsalela ze-asilic acid kwi-glycoproteins kunye ne-glycolipids.Xa ezi enzyme zisebenza kwi-2'- (4-Methylumbelliferyl) -alpha-DN-acetylneuraminic acid ityuwa yesodium, ikhupha imveliso ye-fluorescent eyaziwa ngokuba yi-4-methylumbelliferon.

I-fluorescence eyenziwa yi-compound inokulinganiswa kunye nokulinganisa, inika ulwazi malunga nomsebenzi we-neuraminidase enzymes.Oku kuluncedo ngakumbi kwisifundo sezifo ezahlukeneyo kunye neemeko ezinxulumene ne-aberrant sialic acid metabolism.

Ikhompawundi ikwasetyenziselwa iinjongo zokuxilonga, ezifana nokufumanisa usulelo lwentsholongwane olubandakanya umsebenzi we-neuraminidase.Kolu vavanyo, ikhompawundi isetyenziselwa ukuchonga ubukho beentlobo ezithile zentsholongwane okanye ukuvavanya ukusebenza kwe-neuraminidase inhibitors kunyango lwe-antiviral.

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I-Neuraminidase Activity Assay: Le khompawundi iqhele ukusetyenziselwa ukulinganisa umsebenzi we-neuraminidase enzymes kwiisampulu zebhayoloji.Ngokubeka iliso kwi-fluorescence eyenziwe, abaphandi banokumisela inqanaba lomsebenzi we-neuraminidase, onokunceda ekufundeni izifo ezahlukeneyo kunye neemeko.

Ukufunyaniswa koSulelo lweNtsholongwane: Uninzi lwezifo ezibangelwa yintsholongwane, kubandakanywa umkhuhlane, zibandakanya umsebenzi we-neuraminidase.Le khompawundi ingasetyenziselwa ukufumanisa kunye nokulinganisa ubukho beentlobo ezithile zentsholongwane ngokulinganisa umsebenzi we-fluorescent.Iluncedo ngakumbi ekuvavanyeni ukusebenza kwe-neuraminidase inhibitors kunyango lwe-antiviral.

Uhlalutyo lwe-Glycosylation: I-asilic acid iyinxalenye ebalulekileyo ye-glycoproteins kunye ne-glycolipids.Ngokubandakanya i-2'- (4-Methylumbelliferyl) -alpha-DN-acetylneuraminic acid ityuwa yesodium kwiimvavanyo, abaphandi banokufumana ulwazi kwi-asilic acid metabolism, iipatheni ze-glycosylation, kunye neenkqubo ezinxulumene ne-physiological.

Ukufunyanwa kweziyobisi: I-Neuraminidase inhibitors luhlobo lwamachiza asetyenziswa kunyango losulelo lwentsholongwane.Le khompawundi ingasetyenziswa kwizifundo zokufunyanwa kweziyobisi, ukunceda abaphandi ukuba bachonge kwaye bavavanye ii-inhibitors ezinokubakho zomsebenzi we-neuraminidase.

Ukupakishwa kweMveliso:

Iinkcukacha ezongezelelweyo:

Ukuqamba	I-C21H26NNAO11
Isivavanyi	99%
Imbonakalo	Umgubo omhlophe
Inombolo yeCAS.	76204-02-9
Ukupakisha	Incinci kwaye ininzi
Beka ubomi kwishelufa	iminyaka eyi-2
Ugcino	Gcina kwindawo epholileyo neyomileyo
Isiqinisekiso	ISO.