2,3,5,6-Di-O-isopropylidene-α-D-mannofuranose CAS:14131-84-1

Isiphumo se-2,3,5,6-Di-O-isopropylidene-α-D-mannofuranose kukubonelela ngokhuseleko kumaqela e-hydroxyl kwimolekyuli ye-mannose. Le khompawundi yenza ikhaka elikhuselayo elijikeleze amaqela e-hydroxyl kwiindawo 2, 3, 5, kunye ne-6, lithintela ukuba kwenzeke iimpendulo ezingafunekiyo kwezo ndawo. Ukusetyenziswa okuphambili kwe-2,3,5,6-Di-O-isopropylidene-α-D-mannofuranose kukwicandelo le-carbohydrate chemistry kunye nokwenziwa kwayo. Iicarbohydrate ziimolekyuli ezibalulekileyo ezibandakanyeka kwiinkqubo ezahlukeneyo zebhayoloji ezifana nokuqondwa kweeseli-iiseli, ukuhanjiswa kweeseli, kunye nokuphendula komzimba. Ngokukhusela ngokukhetha amaqela athile e-hydroxyl kwimolekyuli ye-mannose, iingcali zamachiza zinokulawula kwaye ziguqule amanye amaqela asebenzayo ngaphandle kokuchaphazela ii-hydroxyls ezikhuselweyo. Le khompawundi ifumana uncedo ekuhlanganisweni kweecarbohydrates ezintsonkothileyo kunye nee-glycoconjugates. IiGlycoconjugates ziimolekyuli eziqulathe i-carbohydrate moiety enamathele kwenye imolekyuli, njengeproteni okanye i-lipid. Ezi molekyuli zidlala indima ebalulekileyo kwiinkqubo zebhayoloji, kubandakanya ukunamathela kweseli, impendulo yomzimba, kunye nokuqondwa kwezifo. Ngokusebenzisa i-2,3,5,6-Di-O-isopropylidene-α-D-mannofuranose, abaphandi banokuzisa utshintsho kwiindawo ezithile zemolekyuli ye-mannose ngaphakathi kwe-glycoconjugate, ngaphandle kokuphazamisa amaqela e-hydroxyl akhuselweyo. Oku kwenza kube lula ukwenziwa kwee-glycoconjugates ezenzelwe wena kwiindlela ezahlukeneyo zokusebenza, ezinje ngophuhliso lwamayeza, ukuxilongwa, kunye noyilo lwegonyo. Ngamafutshane, isiphumo se-2,3,5,6-Di-O-isopropylidene-α-D-mannofuranose kukukhusela amaqela e-hydroxyl kwimolekyuli ye-mannose, kwaye ukusetyenziswa kwayo kusekwe ekuhlanganisweni kwee-carbohydrates ezintsonkothileyo kunye nee-glycoconjugates ezinokusetyenziswa kwiindawo ezahlukeneyo zophando kunye noshishino.