Empagliflozin CAS:864070-44-0 Umniki-mpahla

I-Empagliflozin yinoveli, inamandla kwaye ikhetha i-SGLT-2 inhibitor, iphucula ulawulo lwe-glycemic kunye neempawu ze-metabolic syndrome kwiimpuku zesifo seswekile. ibangela ukuba iswekile egazini ikhutshwe yizintso kwaye ikhutshwe kumchamo.I-Empagliflozin inokubangela ukungabikho kwamanzi kwaye iholele ekunciphiseni uxinzelelo lwegazi, okukhokelela kwizigulane ezinesiyezi okanye ukuphelelwa amandla kunye nokunciphisa umsebenzi wezintso.Umngcipheko wezigulane ezikhulileyo, ngakumbi ezo zingasebenzi kakuhle kwi-renal kunye ne-diuretics, zibonakala zinkulu.I-FDA idinga u-Boehring no-Eli Lilly ukuba baqhube izifundo ezine emva kokuthengisa: izilingo eziqhubekayo zeziphumo ze-cardiovascular, i-pharmacokinetics yabantwana kunye nezilingo ze-pharmacodynamics, ukhuseleko lwabantwana kunye nokusebenza kakuhle. izilingo, uvavanyo lwetyhefu lwechiza (ingakumbi isiphumo sokusebenza kwezintso, ithambo kunye nokukhula kunye nophuhliso).