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I-Semaglutide CAS: 910463-68-2 uMboneleli woMvelisi
I-Semaglutide liyeza elichasayo lesifo seswekile elithengiswa phantsi kwamagama e-brand njenge-Ozempic, i-Wegovy, kunye ne-Rybelsus.Isetyenziselwa ukuphatha uhlobo lwe-2 yeswekile kunye nokulawula ubunzima obungapheliyo.Ichiza lisebenza ngokufana ne-glucagon-like peptide-1 (GLP-1) ngokwandisa ukukhutshwa kwe-insulin, okukhokelela ekuphuculweni kwemetabolism yeswekile.Isasazwa njenge-metered subcutaneous injection kwipeni ezaliswe kwangaphambili, okanye njengefom yomlomo.Enye yeenzuzo zayo ngaphezu kwamanye amachiza e-antidiabetic kukuba inexesha elide lesenzo, ngoko ke, isitofu esikanye kuphela ngeveki sanele.
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I-Solifenacin Succinate CAS: 242478-38-2 uMboneleli woMvelisi
I-Solifenacin succinate iyeza le-antimuscarinic elisetyenziselwa ukunyanga i-bladder esebenzayo ebangela iimpawu zokuphindaphinda, ukukhawuleza, okanye ukungazinzi.I-Solifenacin yi-M3 ye-muscarinic receptor antagonist eyaphuhliswa kwaye yaqaliswa ukunyangwa kwe-bladder esebenzayo (pollakiuria) eYurophu.Ii-receptors ze-M3 ziye zabandakanyeka kwi-neurally evoked smooth muscle contractions of the bladder, kunye ne-M2 receptors baye bakrokrelwa ukuba badlala indima ngenxa yokulawula kwabo kwi-detrusor muscle.
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N-Acetyl-L-Arginine CAS:155-84-0 uMboneleli woMvelisi
N-Acetyl-L-Arginineayibalulekanga amino acid kubantu abadala, kodwa iveliswa ngokucothayo emzimbeni.Yi-amino acid ebalulekileyo kwiintsana kunye nabantwana abancinci, kwaye inesiphumo esithile sokukhupha.Ikhona kwisixa esikhulu kwiprotamine, njl.Kwiimeko eziqhelekileyo, umzimba ngokwawo unokuvelisa i-L-arginine eyaneleyo.
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I-L-Citrulline CAS: 372-75-8 uMboneleli woMvelisi
I-L-citrulline yi-L-enantiomer ye-citrulline.Inendima njenge-EC 1.14.13.39 (nitric oxide synthase) inhibitor, i-agent ekhuselayo, i-nutraceutical, i-micronutrient, i-metabolite yabantu, i-Escherichia coli metabolite, i-Saccharomyces cerevisiae metabolite kunye ne-metabolite ye-mouse.Yi-enantiomer ye-D-citrulline.Yi-tautomer ye-L-citrulline zwitterion.
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I-Chrysin CAS: 480-40-0 uMboneleli woMvelisi
I-Chrysin yi-flavonoid yendalo ene-antioxidant, i-anti-inflammatory, kunye ne-anticancer properties.Ivimba i-COX-2 i-gene expression, i-PGE2 yokuvelisa, kunye nokwakheka kwe-hydroxyl radical in LPS-induced RAW 264.7 cells.I-Chrysin inqanda i-insulin-induced expression ye-HIF-1α (~ 50% kwi-10 μM) kumhlaza we-prostate yabantu i-DU145 iiseli kunye neebhloko ze-DU145 xenograft-induced angiogenesis in vivo.Kwimodeli yemouse yokulimala kwe-ischemia / i-reperfusion, i-chrysin yehla i-pro-inflammatory gene expression kunye noxinzelelo lwe-oxidative, okubangelwa ukunciphisa umthamo we-infarct kunye neziphene ze-neurological.
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I-Itraconazole CAS: 84625-61-6 uMboneleli woMvelisi
I-Itraconazole yi-clotrimazole eyenziwe ngokwenziwa, ibe yinto ebanzi yokwenziwa kwe-antifungal agent.I-spectrum yayo ye-antimicrobial kunye ne-antimicrobial mechanism ifana ne-clotrimazole, kodwa inomsebenzi onamandla wokulwa ne-Aspergillus.Isebenzisa impembelelo yayo yokuchasana nokungunda ngokutshintsha i-membrane yeseli yokungunda ikwazi ukungena kunye nomsebenzi we-antibacterial ngokuchasene neentsholongwane zefungal ezingaphezulu kunye nezinzulu.I-spectrum yayo ye-antibacterial ibanzi kwaye inamandla kune-ketoconazole, ikwazi ukuvimbela i-ergosterol synthesis ye-membrane ye-fungal cell, ngaloo ndlela idlala umphumo we-antifungal.
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I-Piracetam CAS: 7491-74-9 uMboneleli woMvelisi
I-Piracetam yi-organonitrogen compound kunye ne-organooxygen compound.Isebenza ngokunxulumene ne-alpha-amino acid.I-compound ecetywayo ukuba ibe yi-nootropic kunye ne-neuroprotective agent.I-Piracetam yi-agent ye-nootropic enesalathisi njengonyango oluncedisayo lwe-myoclonus yemvelaphi ye-cortical, kunye ne-tardive dyskinesia.
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Ityuwa yePyrroloquinoline Quinone disodium CAS:122628-50-6
Ityuwa yePyrroloquinoline quinone disodium yikhompawundi yequinone enyibilikayo emanzini enomthamo owomeleleyo wokulwa ne-antioxidant.Le mveliso ngumgubo obomvu obomvu obomvu.Ikwahlukanisiwe kwiinkcubeko zebhaktheriya ye-methylotrophic kunye nezicubu zezilwanyana ezincancisayo.Esi sondlo sibalulekileyo sibalulekile kwizilwanyana ezanyisayo, sidlala indima ebalulekileyo ekwandiseni ukusebenza kwamajoni omzimba.
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I-Cysteine CAS: 52-90-4 uMboneleli woMvelisi
I-L-Cysteine yenye ye-20 yendalo ye-amino acids kwaye, ngaphandle kwe-methionine, kuphela equlethe isulfure.Yi-thiol-equlathe i-amino acid engeyomfuneko edityanisiweyo ukuze yenze i-Cystine.I-amino acid engabalulekanga yesulfure-equkethe i-amino acid kubantu, ehambelana ne-cystine, i-Cysteine ibalulekile kwi-protein synthesis, i-detoxification, kunye nemisebenzi eyahlukeneyo ye-metabolic.Ifunyenwe kwi-beta-keratin, iprotheni ephambili kwizipikili, ulusu, kunye neenwele, i-cysteine ibalulekile kwimveliso ye-collagen, kunye nokuqina kwesikhumba kunye nokuthungwa.
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I-Olmesartan CAS: 144689-24-7 uMboneleli woMvelisi
I-Olmesartan medoxomil,phenyl]phenyl]methyl]imidazole-4-carboxylate (i-Benicar, i-Olmetec) isebenzisa inkqubo ye-tetrazolering njengenkqubo yayo ye-acidic, ethatha inxaxheba kwi-inreceptor binding.Xa ilawulwa kwisigulane, ichiza ngokukhawuleza kwaye ngokupheleleyo i-bioactivated yi-ester hydrolysis ye-medoxomil ngexesha lokufunxa kwi-gastrointestinaltract.I-Olmesartan yi-biphenylyltetrazole.Inendima njenge-arhente ye-antihypertensive kunye ne-angiotensin receptor antagonist.
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Tirzepatide CAS:2023788-19-2 uMboneleli woMvelisi
I-Tirzepatide yaphuhliswa njenge-agonist emibini kuzo zombini i-GLP-1 kunye ne-gastric inhibitory polypeptide (GIP) receptors (Frias et al., 2018).Ngokufana ne-GLP-1, i-GIP yi-hormone ye-incretin esebenza ukukhupha i-insulin secretion.I-Tirzepatide ikwisigaba sesi-3 sophuhliso lwabantu abadala abatyebileyo okanye abatyebileyo kunye ne-comorbidity ehambelana nobunzima kwaye ngoku iphantsi kohlaziyo lolawulo njengonyango lwabantu abadala abanesifo sikashukela sohlobo lwe-2. .Ikwaphononongwa njengonyango olunokubakho lwe-steatohepatitis engeyiyo utywala (NASH) kunye nokusilela kwentliziyo kunye neqhezu le-ejection eligciniweyo (HFpEF).
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I-Aspartic Acid CAS: 56-84-8 uMboneleli woMvelisi
Aspartic Acidisetyenziswa njengesongezelelo sokutya, inokudityaniswa neeminerali ukwenza iikhompawundi ezifana ne-potassium aspartate, i-copper aspartate, i-manganese aspartate, i-magnesium aspartate, i-zinc aspartate kunye nokunye.Ukonyusa ukufunxwa, kunye nokusetyenziswa okunokwenzeka, kwezi zimbiwa ngokongezwa kweaspartate kubangela izibonelelo ezithile zempilo.Iimbaleki ezininzi zisebenzisa izongezelelo zeminerali ezisekwe kwi-L-aspartic acid ngomlomo ukukhulisa amandla abo okusebenza.I-Aspartic acid kunye ne-glutamic acid idlala indima ebalulekileyo njenge-asidi ngokubanzi kumaziko asebenzayo e-enzyme, kunye nokugcina i-solubility kunye ne-ionic character of proteins.
