I-Sitagliptin Phosphate CAS: 654671-78-0 uMboneleli womvelisi

I-Sitagliptin Phosphateyinoveli yokuqala ye-dipeptidyl peptidase IV inhibitor esuka kwi-Merck yonyango lwe-2 yeswekile ngaphandle kokufumana ubunzima kunye nezehlo ze-hypoglycemia zazifana ne-placebo.I-Sitagliptin isebenza ngokuphucula inkqubo ye-incretin yomzimba, enceda ukulawula i-glucose ngokuchaphazela iiseli ze-β kunye ne-α kwi-pancreas.

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ISitagliptin Phosphate sisithinteli se-trizolopyrazine dipeptidyl peptidase IV.ISitagliptin isandula kuvunywa kunyango lwesifo seswekile sohlobo lwesi-II. ISitagliptin phosphate yidipeptidyl peptidase Ⅳ(DDP-4) inhibitor udidi lwamachiza aphuhliswe yinkampani yaseJamani iMerck kwaye kuqala yafumana imvume yoLawulo lokuTya kunye neChiza e-US kunyango lodidi lwesi-2. Isifo seswekile, lichiza elitsha le-antidiabetic, linokuphucula amandla omzimba wokunciphisa amanqanaba aphezulu eswekile yegazi, kunye nokwanda ngokwendalo okwenzeka kwi-incretin ngokuthintela umsebenzi wale enzyme, kubandakanywa amanqanaba e-glucagon-like peptide 1 kunye ne-glucose exhomekeke kwi-insulinotropic. i-peptide, ngaloo ndlela ibangela i-pancreas ukuba iphucule imveliso ye-insulin kwaye iyeke ukuveliswa kweglucose esibindini, kwaye ekugqibeleni inciphise isiphumo seklinikhi sokuxinana kweglucose yegazi.

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Iinkcukacha ezongezelelweyo:

Ukuqamba	C16H15F6N5O.H3PO4
Isivavanyi	99%
Imbonakalo	Mhlophe ukuya kumgubo oMhlophe
Inombolo yeCAS.	654671-78-0
Ukupakisha	25KG
Beka ubomi kwishelufa	iminyaka eyi-2
Ugcino	Gcina kwindawo epholileyo neyomileyo
Isiqinisekiso	ISO.