Umthengisi weSitagliptin Phosphate CAS: 654671-78-0

I-Sitagliptin Phosphate sisithinteli se-trizolopyrazine dipeptidyl peptidase IV. I-Sitagliptin isandula ukuvunywa kunyango lwesifo seswekile sohlobo lwesibini. I-Sitagliptin phosphate ludidi lwamayeza okuthintela i-dipeptidyl peptidase Ⅳ(DDP-4) oluphuhliswe yinkampani yaseJamani iMerck kwaye okokuqala yafumana imvume ye-US Food and Drug Administration yokunyanga isifo seswekile sohlobo lwesibini, sisiyobisi esitsha esilwa nesifo seswekile, sinokuphucula amandla omzimba okunciphisa amanqanaba aphezulu eswekile egazini, kunye nokwanda kwe-incretin okwenzeka ngokwemvelo ngokuthintela umsebenzi wale enzyme, kubandakanya amanqanaba e-glucagon-like peptide 1 kunye ne-glucose-dependent insulinotropic peptide, ngaloo ndlela ibangela ukuba i-pancreas iphucule imveliso ye-insulin kwaye iyeke ukuveliswa kweswekile esibindini, kwaye ekugqibeleni inciphise impembelelo yeklinikhi yoxinzelelo lweswekile egazini.