β-Nicotinamide Mononucleotide CAS:1094-61-7

I-Nicotinamide mononucleotide (NMN), imveliso ye-NAMPT yokusabela kunye ne-NAD + ephakathi, iphucula ukunganyamezeli kwe-glucose ngokubuyisela amanqanaba e-NAD + kwiigundane ze-HFD-induced T2D.I-NMN ikwaphucula ubuntununtunu be-insulin ye-hepatic kwaye ibuyisela ukubonakaliswa kofuzo okunxulumene noxinzelelo lwe-oxidative, impendulo yokuvuvukala, kunye nesigqi se-circadian, ngokuyinxenye ngokusebenzisa i-SIRT1 kusebenze.I-NMN isetyenziselwa ukufunda i-motifs ebophelelayo ngaphakathi kwe-RNA aptamers kunye neenkqubo zokuvula i-ribozyme ezibandakanya i-β-nicotinamide mononucleotide (β-NMN) -i-RNA fragments.

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I-β-Nicotinamide mononucleotide (NMN) isetyenziselwa ukufunda i-motifs ebophelelayo ngaphakathi kwe-RNA aptamers kunye neenkqubo zokuvula i-ribozyme ezibandakanya i-β-nicotinamide mononucleotide (β-NMN) -i-RNA fragments.I-NMN yi-nucleotide evela kwi-ribose kunye ne-nicotinamide.I-Niacinamide (i-nicotinamide,) iphuma kwi-vitamin B3, eyaziwa ngokuba yi-niacin.) Njenge-precursor ye-biochemical ye-NAD +, inokuba luncedo ekuthinteleni i-pellagra.
I-β-Nicotinamide mononucleotide yindawo ephakathi kwi-biosynthesis ye-nicotinamide adenine dinucleotide (NAD+).I-Nicotinamide phosphoribosyltransferase (i-Nampt) ikhuthaza ukuxinana kwe-nicotinamide nge-5-phosphoribosyl-1-pyrophosphate ukuvelisa i-β-NMN, ethi emva koko iguqulelwe kwi-NAD+ nge-β-NMN adenyltransferase.At 50-MN-beta isetyenzisiwe I-NAD biosynthesis kunye ne-glucose-evuselelwe ukukhuselwa kwe-insulin kwimodeli ye-Nampt +/- mouse yesifo se-metabolic, ebonisa indima ye-Nampt kwi-cell function ye-β.

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Ukuqamba	I-C11H15N2O8P
Isivavanyi	99%
Imbonakalo	Umgubo omhlophe
Inombolo yeCAS.	1094-61-7
Ukupakisha	25KG
Beka ubomi kwishelufa	iminyaka eyi-2
Ugcino	Gcina kwindawo epholileyo neyomileyo
Isiqinisekiso	ISO.