2-(3,5-Dimethyl-4-(2-(pyrrolidin-1-yl)ethoxy)phenyl)-5,7-dimethoxyquinazolin-4(3H)-one CAS:1044871-04-6

Uncedo olunemiba emininzi lwe-2-(3,5-Dimethyl-4-(2-(pyrrolidin-1-yl)ethoxy)phenyl)-5,7-dimethoxyquinazolin-4(3H)-one lukwizicelo zalo ezinokubakho kuphando nophuhliso lwamayeza. Njengenxalenye ephambili, le khompawundi inegalelo ekuhlanganisweni kwamayeza amatsha kunye neemolekyuli ezisebenzayo kwi-pharmacologically. Abaphandi basebenzisa iimpawu zayo ezizodwa zesakhiwo ukuphonononga indima yayo ekuphuhliseni unyango olujolise kwizifo ezahlukeneyo, okunokukhokelela ekudalweni kweemveliso ezintsha zamayeza ezisebenza ngcono kunye neempawu eziphuculweyo ze-pharmacokinetic. Ngaphezu koko, le khompawundi inokufumana ukusetyenziswa kwikhemistri yamayeza kuyilo kunye nokuhlanganiswa kweekhompawundi ezinemisebenzi ethile yebhayoloji. Iimpawu zayo zesakhiwo zenza ukuba ifaneleke ukuphononongwa kobudlelwane besakhiwo-nomsebenzi, inceda ekuchongweni kweekhompawundi ze-lead ezinokubakho zophuhliso lwamayeza. Ukongeza, ingasebenza njengebhloko yokwakha exabisekileyo yokuhlanganiswa kweemolekyuli ezahlukeneyo ze-organic, inegalelo ekwandiseni indawo yeekhemikhali ekhoyo yokufunyanwa kwamayeza kunye nokuhlanganiswa kwezinto ze-organic. Lilonke, i-2-(3,5-Dimethyl-4-(2-(pyrrolidin-1-yl)ethoxy)phenyl)-5,7-dimethoxyquinazolin-4(3H)-one inika amandla abalulekileyo ekuqhubeleni phambili uphando lwezamayeza, ikhemistri yezamayeza, kunye nokudalwa kweekhompawundi ezifanelekileyo kwizamayeza, ikubeka njengexabiso elixabisekileyo kuphando lwesayensi kunye nokuvelisa izinto ezintsha kumacandelo ezamayeza kunye neekhemikhali.