2′,6′-DiMethylcarbonylphenyl-10-sulfopropylacridiniuM-9-carboxylate 4′-NHS Ester CAS:194357-64-7 Umfanekiso obonisiweyo

I-2′,6′-DiMethylcarbonylphenyl-10-sulfopropylacridiniuM-9-carboxylate 4′-NHS Ester CAS:194357-64-7

I-2′,6′-DiMethylcarbonylphenyl-10-sulfopropylacridinium-9-carboxylate I-4′-NHS ester yikhemikhali enesakhiwo semolekyuli esintsonkothileyo. Iqulethe iqela le-sulfopropylacridinium kunye neqela elisebenzayo le-carboxylate ester. Ubukho be-ester moiety bubonisa ukuba iyasabela kwaye ingasetyenziswa njenge-arhente yokulebhelisha okanye yokuguqula ii-biomolecules.

Iqela le-sulfopropylacridinium yekhompawundi licebisa ukuba inokuba nokusetyenziswa okunokwenzeka kwiimvavanyo ezisekelwe kwi-fluorescence, apho ingasetyenziswa njenge-fluorescent probe okanye idayi yokufumanisa nokuhlalutya ii-biomolecules. Isenokuba nokubaluleka kwizifundo zeenkqubo zeseli, ezifana ne-intracellular calcium signaling.

Ukufakwa kweqela le-NHS ester kubonisa ukuba inokusabela kunye nee-amines eziphambili, ezifana nezo zifumaneka kwiiproteni okanye iipeptides, ukuze zenze ii-amide bonds ezizinzileyo. Olu hlobo lokusabela lwenza ukuba lube luncedo kwizicelo ze-bioconjugation, apho lunokusetyenziselwa ukulebhelisha okanye ukuguqula ii-biomolecules kunye nezinye iimolekyuli ezisebenzayo, ezifana nee-fluorophores okanye iithegi.

Oda okanye Cela iKoteshini

Iinkcukacha zeMveliso

Iithegi zeMveliso

Ukusetyenziswa kunye nesiphumo

Ngokubanzi, iikhompawundi eziqulethe i-acridinium derivatives kunye namaqela e-NHS ester functional zinokuba nezicelo ezahlukeneyo, ingakumbi kwicandelo le-bioconjugation kunye ne-fluorescence labeling. Zisetyenziswa kakhulu ekubhaleni ii-biomolecules, ezifana neeproteni, ii-peptides, kunye nee-nucleic acids, kunye namaqela e-fluorescent okanye amanye amaqela asebenzayo.

Iqela le-NHS ester livumela ii-activations ezikhethiweyo zokudibanisa kunye nee-amines eziphambili, ezifumaneka rhoqo kwi-biomolecules. Oku kwenza ukuba idayi ye-fluorescent inamathele kwi-molecule ekujoliswe kuyo, okuvumela ukubonakala okanye ukubonwa kwizicelo ezahlukeneyo zebhayoloji ezifana ne-fluorescence microscopy, i-flow cytometry, okanye i-enzyme-linked immunosorbent assays (ELISA).

Ukupakisha imveliso:

Iinkcukacha ezongezelelweyo:

Ukwakhiwa	C30H26N2O9S
Uvavanyo	99%
Inkangeleko	Umgubo omhlophe
Inombolo ye-CAS	194357-64-7
Ukupakisha	Encinci kwaye ininzi
Beka ubomi kwishelufa	iminyaka eyi-2
Indawo yokugcina izinto	Gcina kwindawo epholileyo neyomileyo
Isiqinisekiso	I-ISO.