I-Boc-Asp(OBzl)-OSu CAS:13798-75-9

I-Boc-Asp(OBzl)-OSu isetyenziswa kakhulu kwi-peptide synthesis njenge-coupling reagent yokungeniswa okukhethekileyo kwe-L-aspartic acid kwii-peptide chains. Njenge-N-hydroxysuccinimide (NHS) ester derivative, inceda ukwakheka kwe-stable amide bonds phakathi kweqela le-carboxyl le-Boc-Asp(OBzl) kunye namaqela e-amino kwezinye iimolekyuli, okuvumela ukuhlanganiswa kwe-peptide ngokuchanekileyo nangokulawulwayo. Oku kubalulekile ekufumaneni amayeza kunye nophuhliso, kunye nezifundo ze-biochemical ezijolise ekuqondeni ukusebenzisana kweproteni kunye neendlela zokubonisa. Ngaphezu koko, i-Boc-Asp(OBzl)-OSu idlala indima ebalulekileyo ekuguqulweni kweproteni kunye neepeptides kwindawo ethile kuphando olwahlukeneyo kunye nokusetyenziswa kwezonyango. Ubunyulu bayo obuphezulu kunye nomgangatho ohambelanayo kuqinisekisa ukuthembeka kunye nokuphindaphinda kwiinkqubo zophando, okwenza ukuba ibe sisixhobo esibalulekileyo kwizazinzulu kunye nabaphandi kwiindawo ezahlukeneyo, ukusuka kuphando olusisiseko ukuya kuphuhliso lwamayeza amatsha kunye neekhompawundi ze-bioactive. Ngamafutshane, iBoc-Asp(OBzl)-OSu ibalulekile ekuphuculeni ukufunyanwa kwesayensi kunye nezonyango ngokuvumela ukuhlanganiswa kweepeptides ezintsonkothileyo ezineempawu ezilungiselelwe wena, ekugqibeleni zixhasa uphuhliso lwamayeza amatsha kunye neearhente zonyango. Ukuguquguquka kwayo kunye nokusetyenziswa kwayo ngokubanzi kuphando lwamayeza kugxininisa ukubaluleka kwayo njengesixhobo esixabisekileyo kwizazinzulu kunye nabaphandi kwihlabathi liphela.