Boc-D-Leu-OH·H2O CAS:16937-99-8

I-Boc-D-Leu-OH·H2O isetyenziswa kakhulu kwi-solid-phase peptide synthesis ukwenza iipeptides ezenzelwe wena ngokwesiko ezine-sequences kunye nemisebenzi ethile. Njengendlela ekhuselekileyo ye-D-leucine, ivumela ukungeniswa okulawulwayo kwee-D-leucine residues kwi-peptide chain ekhulayo, ithintela iimpendulo ezingafunekiyo kwaye ivumela ukuhlanganiswa kweepeptides ezintsonkothileyo ezineempawu ezilungiselelwe wena. Kwi-bioconjugation kunye ne-chemical biology, i-Boc-D-Leu-OH·H2O isebenza njengebhloko yokwakha eguquguqukayo yokwenza iipeptides ze-bioactive, ii-probes ezibhalwe amagama, kunye ne-peptide-based therapeutics. Ukusetyenziswa kwayo kwenza utshintsho oluchanekileyo lweepeptides kunye neeproteni, kunceda uphuhliso lweemolekyuli ezininzi ezinomsebenzi ozinzileyo, ukucaciswa kwethagethi, okanye amandla okucinga kwizicelo ezahlukeneyo ze-biomedical. Ngaphezu koko, ekufumaneni amayeza kunye nophuhliso lonyango, i-Boc-D-Leu-OH·H2O isetyenziswa ukwenza ii-peptide conjugates kunye neepeptides eziguquliweyo ezineeprofayili ze-pharmacokinetic eziphuculweyo kunye nemisebenzi yebhayoloji. Olu tshintsho lunokuphucula ukusebenza kakuhle, ukukhetha, kunye nokuhanjiswa kwamayeza asekelwe kwi-peptide, okufaka isandla ekuphuculeni amayeza achanekileyo kunye neendlela zonyango ezijolise kuzo. Ngokubanzi, ukuthembeka kunye nokuguquguquka kwe-Boc-D-Leu-OH·H2O ekuqulunqweni kwe-peptide kunye ne-bioconjugation kwenza ukuba ibe sisixhobo esibalulekileyo sokuqhubela phambili uphando ekufumaneni amayeza, i-chemical biology, kunye ne-proteomics, okubonelela ngamathuba ahlukeneyo okuphuhlisa usetyenziso olutsha lwe-biomedical.