I-Boc-Lys(Z)-OSu CAS:34404-36-9

I-Boc-Lys(Z)-OSu isetyenziswa kakhulu kwiinkqubo zokuguqula i-bioconjugation kunye ne-peptide. Kwi-peptide synthesis, isetyenziselwa ukungenisa ii-lysine residues kwiindawo ezithile ngaphakathi kolandelelwano lwe-peptide, okuvumela ukunamatheliswa kwamaqela asebenzayo, iilebheli, okanye ezinye iimolekyuli zezicelo ezahlukeneyo. Olu tshintsho lukhethayo luvumela ukudalwa kwee-peptides ezisebenzayo ezininzi ezineempawu ezilungiselelweyo, ezinje ngokuzinza okuphuculweyo, ukucaciswa kwethagethi, okanye amandla okufota. Ngaphezu koko, kuphando lwe-proteomics, i-Boc-Lys(Z)-OSu iququzelela ukulebheliswa kweeproteni kunye neepeptides kwindawo ethile ukuze kuhlalutywe ulwakhiwo, izifundo zokunxibelelana, kunye novavanyo lwe-proteomic olusekwe kwi-mass spectrometry. Ukunamatheliswa okulawulwayo kwe-Boc-Lys(Z)-OSu kwi-lysine residues kwenza ukuba kuchazwe ngokuchanekileyo kwaye kuhlalutywe ukusebenza kweeproteni kunye neepeptides, ngaloo ndlela kuncedisa ekuphuhliseni ukuqonda iinkqubo zebhayoloji kunye neendlela zesifo. Ngaphezu koko, kwicandelo lophuhliso lwamayeza, iBoc-Lys(Z)-OSu idlala indima ebalulekileyo ekudibaniseni iiarhente zonyango kwiipeptides okanye iiproteni, ngaloo ndlela idala iinkqubo zokuhambisa amayeza ekujoliswe kuzo, ii-antibody-drug conjugates, okanye izakhiwo zevaccine ezineeprofayili ze-pharmacokinetic eziphuculweyo kunye neziphumo ezincitshisiweyo ezingajoliswanga. Ngokubanzi, ukuguquguquka kweBoc-Lys(Z)-OSu kunye nokuthembeka ekuguqulweni kwepeptide kunye ne-bioconjugation kwenza ukuba ibe sisixhobo esibalulekileyo sokuqhubela phambili uphando ekufumaneni amayeza, i-chemical biology, kunye ne-proteomics, inika amathuba ahlukeneyo okuphuhlisa usetyenziso olutsha lwe-biomedical.