Boc-Nle-OH·DCHA CAS:21947-32-0

I-Boc-Nle-OH·DCHA isetyenziswa kakhulu kwi-solid-phase peptide synthesis ukwenza iipeptides ezenzelwe wena ngokwesiko ezine-sequences kunye nemisebenzi ethile. Njengendlela ekhuselweyo ye-norleucine, ivumela ukungeniswa okulawulwayo kwee-norleucine residues kwi-peptide chain ekhulayo, ithintela iimpendulo ezingafunekiyo kwaye ivumela ukuhlanganiswa kweepeptides ezintsonkothileyo ezineempawu ezilungiselelwe wena. Kwi-bioconjugation kunye ne-chemical biology, i-Boc-Nle-OH·DCHA isebenza njengebhloko yokwakha eguquguqukayo yokwenza iipeptides ze-bioactive, ii-probes ezibhalwe amagama, kunye ne-peptide-based therapeutics. Ukusetyenziswa kwayo kwenza utshintsho oluchanekileyo lweepeptides kunye neeproteni, kunceda uphuhliso lweemolekyuli ezininzi ezinomsebenzi ozinzileyo, ukucaciswa kwethagethi, okanye amandla okuthatha imifanekiso kwizicelo ezahlukeneyo ze-biomedical. Ngaphezu koko, ekufumaneni amayeza kunye nophuhliso lwezonyango, i-Boc-Nle-OH·DCHA isetyenziselwa ukudala ii-peptide conjugates kunye neepeptides ezilungisiweyo ezineeprofayili ze-pharmacokinetic eziphuculweyo kunye nemisebenzi yebhayoloji. Olu tshintsho lunokuphucula ukusebenza kakuhle, ukukhetha, kunye nokuhanjiswa kwamayeza asekelwe kwi-peptide, okufaka isandla ekuphuhliseni amayeza achanekileyo kunye ne-therapeutics ekujoliswe kuyo. Lilonke, ukuthembeka kunye nokuguquguquka kweBoc-Nle-OH·DCHA ekuqulunqweni kwepeptide kunye nokudibanisa izinto eziphilayo kwenza ukuba ibe sisixhobo esibalulekileyo sokuqhubela phambili uphando ekufumaneni iziyobisi, ibhayoloji yamachiza, kunye neproteomics, nto leyo enika amathuba ahlukeneyo okuphuhlisa usetyenziso olutsha lwe-biomedical.