I-Boc-Orn(Z)-OH(isiraphu) I-CAS:2480-93-5

I-Boc-Orn(Z)-OH (isiraphu) isetyenziswa kakhulu kwi-solid-phase peptide synthesis ukwenza iipeptides ezenzelwe wena ngokwesiko ezine-sequences kunye nemisebenzi ethile. Njengendlela ekhuselweyo ye-ornithine, ivumela ukufakwa okulawulwayo kwee-ornithine residues kwi-peptide chain ekhulayo, ithintela iimpendulo ezingafunekiyo kwaye ivumela ukwenziwa kweepeptides ezintsonkothileyo ezineempawu ezilungiselelwe wena. Kwi-bioconjugation kunye ne-chemical biology, i-Boc-Orn(Z)-OH (isiraphu) isebenza njengebhloko yokwakha eguquguqukayo yokwenza iipeptides ezisebenzayo, ii-probes ezibhalwe amagama, kunye ne-peptide-based therapeutics. Ukusetyenziswa kwayo kwenza ukuguqulwa okuchanekileyo kweepeptides kunye neeproteni, kunceda uphuhliso lweemolekyuli ezininzi ezinomsebenzi ozinzileyo, ukucaciswa okujoliswe kuko, okanye amandla okucinga kwizicelo ezahlukeneyo ze-biomedical. Ngaphezu koko, ekufumaneni amayeza kunye nophuhliso lonyango, i-Boc-Orn(Z)-OH (isiraphu) isetyenziswa ukwenza ii-peptide conjugates kunye neepeptides eziguquliweyo ezineeprofayili ze-pharmacokinetic eziphuculweyo kunye nemisebenzi yebhayoloji. Olu tshintsho lunokuphucula ukusebenza kakuhle, ukukhetha, kunye nokuhanjiswa kwamayeza asekelwe kwi-peptide, okufaka isandla ekuphuculeni amayeza achanekileyo kunye neendlela zonyango ezijolise kuzo. Ngokubanzi, ukuthembeka kwe-Boc-Orn(Z)-OH (isiraphu) kunye nokuguquguquka kwayo ekuqulunqweni kwe-peptide kunye ne-bioconjugation kwenza ukuba ibe sisixhobo esibalulekileyo sokuqhubela phambili uphando ekufumaneni amayeza, i-chemical biology, kunye ne-proteomics, okubonelela ngamathuba ahlukeneyo okuphuhlisa usetyenziso olutsha lwe-biomedical.