I-Boc-Phe-ONp CAS:7536-56-0

I-Boc-Phe-ONp idlala indima ebalulekileyo ekuhlanganisweni kwe-peptide, ngakumbi ekuhlanganisweni kwe-peptide yesigaba sesisombululo kunye nokuhlanganiswa kwe-peptide yesigaba esiqinileyo (i-SPPS). Njenge-amino acid derivative ekhuselweyo, isebenza njengebhloko yokwakha ebalulekileyo yokufaka iintsalela ze-phenylalanine kwi-peptide sequences. Kwi-SPPS, i-Boc-Phe-ONp isetyenziselwa ukungenisa ngokukhethekileyo iiyunithi ze-phenylalanine ngexesha lokuhlanganiswa kwe-peptide chain kwi-solid supports, ngelixa ekuhlanganisweni kwe-solution-phase, ivumela ukwakheka kweebhondi ze-peptide kwiimpendulo ezisekelwe kwisisombululo. Abaphandi kunye neengcali zezemithi basebenzisa i-Boc-Phe-ONp ukwenza ii-peptides ezenzelwe wena ezine-amino acid sequences ezithile ezilungiselelwe uvavanyo lwebhayoloji, izifundo zesakhiwo, kunye nophuhliso lwamayeza. Ngokusebenzisa i-reactivity yeqela le-4-nitrophenyl ester, banokufikelela ekudibaneni okusebenzayo namaqela e-amino, okukhokelela ekwandiseni okulawulwayo kwee-peptide chain kunye nokuveliswa kwezakhiwo ezahlukeneyo ze-peptide. Ukuguquguquka kwe-Boc-Phe-ONp kuyenza ibe sisixhobo esibalulekileyo kwiinkalo ezahlukeneyo ezifana ne-biochemistry, i-pharmacology, kunye ne-biotechnology. Ukuhambelana kwayo nemigaqo eqhelekileyo yokwenziwa kwepeptide, isivuno esiphezulu, kunye nokusebenza okuthembekileyo kunegalelo ekusetyenzisweni kwayo ngokubanzi kwiindawo zemfundo nakwimizi-mveliso. Nokuba isetyenziswa kuphando olusisiseko okanye kwimizamo yokufumanisa iziyobisi, iBoc-Phe-ONp inceda ekudalweni kweepeptides ezixhasa ukuqhubela phambili okubalulekileyo kwisayensi yezonyango kunye nokuvelisa izinto ezintsha zonyango.