I-Bz-His-OH CAS:5354-94-9

I-Bz-His-OH yinxalenye ebalulekileyo ekuqulunqweni kwe-peptide, esebenza njengesiseko sokwakha ii-peptides ezineempawu ezithile zesakhiwo kunye nokusebenza. Iqela elikhusela i-benzyl liqinisekisa ukuba intsalela ye-histidine ihlala ingatshintshi ngexesha leenkqubo zokwenziwa kwe-peptide, okuvumela ukuhlanganiswa kwe-peptide ngokuchanekileyo nangokulawulwayo. Le khompawundi ibalulekile ekuyileni ii-peptides ezineempawu ezilungiselelweyo ezifana nokuzinza okuphuculweyo, uvakalelo lwe-pH, okanye ulungelelwaniso lwee-ion zesinyithi, okwenza ukuba ibe sisixhobo esibalulekileyo ekuphuhlisweni kwamayeza. Ukongeza, i-Bz-His-OH isetyenziswa ekudalweni kwamayeza asekelwe kwi-peptide anokusebenza ngcono konyango ngenxa yeempawu zayo ezithile. Ngaphezu koko, kuphando lwe-proteomics kunye ne-biochemical, i-Bz-His-OH ifumana ukusetyenziswa ekufundeni imisebenzi ye-enzyme, ukuphanda iimpawu zokubopha isinyithi, kunye nokuphonononga utshintsho oluxhomekeke kwi-pH kwiiproteni. Iimpawu zayo ezikhethekileyo zivumela abaphandi ukuba baphonononge ubunzima beenkqubo zeseli kunye neendlela zesifo, zinegalelo ekuqhubekeni kokuqonda impilo kunye ne-pathology. Ukuguquguquka kunye nokuhambelana kwekhompawundi neemeko ezahlukeneyo zovavanyo kwenza ukuba ibe yinxalenye ebalulekileyo yokutyhila ubunzima beenkqubo zebhayoloji kunye nokuphuhlisa iindlela zokungenelela ezijolise kwiimeko ezahlukeneyo zonyango. Ngamafutshane, i-Bz-His-OH imele isixhobo esibalulekileyo kubaphandi kwi-peptide synthesis, uphuhliso lwamayeza, kunye nezifundo ze-biochemical, enika amandla okulungisa iipeptides ezineempawu ezithile kunye nokusombulula iindlela ezisisiseko zeenkqubo zebhayoloji, ngaloo ndlela inegalelo ekuphuculeni amayeza kunye ne-biotechnology.