I-Capastat sulfate (i-Capreomycin sulfate) I-CAS:1405-37-4

I-Capastat sulfate (i-Capreomycin sulfate) idlala indima ebalulekileyo ekulawuleni isifo sephepha esinganyangekiyo ngamayeza amaninzi, uhlobo lwesifo sephepha olunganyangekiyo kumayeza aqhelekileyo okulwa nesifo sephepha. Idla ngokusetyenziswa kunye namanye amayeza odidi lwesibini ukujolisa ngempumelelo nokunyanga usulelo lwe-MDR-TB. Ngenxa yomsebenzi wayo wokubulala iintsholongwane kwiintlobo zesifo sephepha seMycobacterium ezinganyangekiyo kumayeza odidi lokuqala afana ne-isoniazid kunye ne-rifampin, i-Capastat sulfate igcinelwe iimeko apho unyango lwe-TB oluqhelekileyo lungasebenzi. Unyango nge-Capastat sulfate ludla ngokwenziwa phantsi kweliso leengcali zempilo ezinamava ekulawuleni isifo sephepha esinganyangekiyo ngamayeza. Umthamo kunye nobude bonyango lwe-Capastat sulfate lulungiselelwe iimfuno zesigulana ngasinye ngokusekelwe kwizinto ezifana nobunzima bosulelo, ubunzima besigulana, kunye nokusebenza kwezintso. Ukujonga rhoqo ukusebenza kwezintso kunye nokuva kubalulekile ngexesha lonyango, njengoko amayeza okubulala iintsholongwane e-aminoglycoside afana ne-Capreomycin anokubangela umonakalo wezintso kunye nokulahlekelwa kukuva. Izigulana ezisebenzisa unyango lwe-Capastat sulfate kufuneka zilandele inkqubo yazo yonyango emiselweyo ngenkuthalo ukuze zifumane iziphumo ezilungileyo kwaye zinciphise umngcipheko wokukhula kokumelana ngakumbi. Ukunamathela kwikhosi epheleleyo yonyango kubalulekile ukuqinisekisa ukupheliswa ngokupheleleyo kwe-MDR-TB kunye nokunciphisa amathuba okuba unyango lungaphumeleli okanye lubuyele umva. Ukubeka esweni ngokusondeleyo naziphi na iziphumo ezimbi kunye novavanyo lokulandelela rhoqo kunye nababoneleli bezempilo kuyacetyiswa ukulawula iziphumo ebezingalindelekanga kunye nokuphucula izibonelelo zonyango zeCapastat sulfate ekulweni nesifo sephepha esinganyangekiyo ngamayeza.