I-Capreomycin sulfate (i-Capastat sulfate) I-CAS:1405-37-4

I-Capreomycin sulfate (i-Capastat sulfate) yinxalenye ebalulekileyo ekulawuleni isifo sephepha esinganyangekiyo ngamayeza amaninzi (i-MDR-TB), ingakumbi xa amayeza okuqala aqhelekileyo okulwa nesifo sephepha engasebenzi kakuhle. Isetyenziswa njengenxalenye yeendlela zonyango ezidibeneyo ukujolisa nokunyanga iintlobo zesifo sephepha iMycobacterium ezinganyangekiyo ngamayeza. Ukunikwa kwe-Capreomycin sulfate kubandakanya inaliti ezifakwa ngaphakathi emzimbeni okanye ezinzulu, ezihlala zijongwa ziingcali zonyango ezinamava ekulawuleni isifo sephepha. Unyango nge-Capreomycin sulfate lufuna ukujongwa ngononophelo ngenxa yeziphumo ezibi ezinokubakho ezinxulumene namayeza okubulala iintsholongwane e-aminoglycoside, kubandakanya ubuthi bezintso kunye nokuphazamiseka kokuva. Umthamo kunye nobude bonyango bucwangciswa ngokwahlukeneyo ngokusekelwe kwimeko yesigulana, ubunzima, ukusebenza kwezintso, kunye nempendulo kunyango. Izigulana ezisebenzisa unyango lwe-Capreomycin sulfate ziyacetyiswa ukuba zilandele ngokungqongqo indlela yonyango emiselweyo ukuze zisebenze kakuhle kwaye zinciphise umngcipheko wokunganyangeki ngakumbi ngamayeza. Ukujonga rhoqo iziphumo ebezingalindelekanga, kunye novavanyo oluqhubekayo lomsebenzi wezintso kunye nokuva, kubalulekile ngexesha lonyango. Intsebenziswano esondeleyo nababoneleli bezempilo kunye nokunamathela ngokungqongqo kwiingcebiso zonyango kubalulekile ukuze kulawulwe ngempumelelo isifo sephepha ngeCapreomycin sulfate, injongo ikukufikelela ekupheliseni ngokupheleleyo i-MDR-TB ngelixa kunciphisa amathuba okuba unyango lungaphumeleli okanye lubuyele esiqhelweni.