I-Colistin sodium methanesulfonate evela kwi-bacillus colistinus CAS:8068-28-8

I-Colistin sodium methanesulfonate isetyenziswa kakhulu ekulawuleni usulelo olukhulu lwebhaktheriya olubangelwa yibhaktheriya ene-gram-negative, ingakumbi iintlobo ezimelana neendidi ezininzi zee-antibiotics. Isetyenziswa kakhulu kwiimeko ze-pneumonia efunyenwe esibhedlele, i-pneumonia enxulumene ne-ventilator, i-sepsis, kunye nosulelo lwe-urinary tract xa ibangelwa zizifo ezinganyangekiyo ngamayeza amaninzi ezifana ne-Pseudomonas aeruginosa, i-Acinetobacter baumannii, kunye ne-Klebsiella pneumoniae. Umthamo ofanelekileyo kunye nolawulo lwe-colistin sodium methanesulfonate kubalulekile ekufezekiseni iziphumo zonyango ezifanelekileyo. Ngenxa yokuba inokubangela ubuthi kunye ne-neurotoxicity, ukujonga ngokusondeleyo umsebenzi wezintso kunye nesimo se-neurological kubalulekile ngexesha lonyango. Uhlengahlengiso lwedosi lunokufuneka ngokusekelwe kumsebenzi wezintso kunye nezinto zesigulana ngasinye. Ngaphambi kokusebenzisa i-colistin sodium methanesulfonate, ababoneleli bezempilo kufuneka bahlole ukuba umzimba osulelekileyo unokuba sengozini kangakanani ukuqinisekisa unyango olufanelekileyo. Iziphumo ezimbi zinokubandakanya ukungasebenzi kakuhle kwezintso, iingxaki zokuphefumla, kunye neempendulo ze-allergy, ezifuna ukubekwa esweni ngononophelo kulo lonke ixesha lonyango. Ngamafutshane, i-colistin sodium methanesulfonate yi-antibiotic ebalulekileyo yokulwa nosulelo olungenazo iigram-negative oluxhathisa amayeza amaninzi kwaye kufuneka igcinelwe iimeko apho kungekho ndlela zimbi ezikhoyo. Ukusetyenziswa kwayo ngobulumko, okukhokelwa yimigaqo yokulawula iintsholongwane, kubalulekile ukugcina ukusebenza kwayo kunye nokuthintela ukuvela kwezinye iindlela zokuxhathisa.