I-Colistin Sulfate CAS: 1264-72-8

I-Colistin sulfate isetyenziswa ekulawuleni usulelo olukhulu lweebhaktheriya olubangelwa ziibhaktheriya ezine-gram-negative ezinganyangekiyo ngamayeza amaninzi. Idla ngokugcinelwa ukunyanga usulelo olufana ne-pneumonia enxulumene nomoya, i-sepsis, usulelo lwendlela yomchamo, kunye nosulelo lwegazi xa lubangelwa ziintsholongwane ezifana ne-Pseudomonas aeruginosa, i-Acinetobacter baumannii, kunye ne-Klebsiella pneumoniae. Umthamo ofanelekileyo kunye nolawulo lwe-colistin sulfate kubalulekile ukuze kufezekiswe iziphumo zonyango ezifanelekileyo ngelixa kunciphisa umngcipheko wemiphumo emibi. Ngenxa yokuba inokubangela ubuthi kunye ne-neurotoxicity, ukujonga ngokusondeleyo umsebenzi wezintso kunye nesimo se-neurological kubalulekile ngexesha lonyango. Uhlengahlengiso lwedosi lungafuneka ngokusekelwe kwiimpawu zesigulana ngasinye kunye nomsebenzi wezintso. Ababoneleli bezempilo kufuneka benze uvavanyo lokuthambekela ngaphambi kokuba baqalise unyango nge-colistin sulfate ukuqinisekisa ukugutyungelwa ngokufanelekileyo kwesidalwa esosulelayo. Iziphumo ezingalunganga zinokubandakanya ukungasebenzi kakuhle kwezintso, iingxaki zokuphefumla, kunye nokusabela kwe-hypersensitivity, okudinga ukubekwa esweni ngononophelo kulo lonke ixesha lonyango. Ukuqukumbela, i-colistin sulfate idlala indima ebalulekileyo ekulweni nosulelo olubangelwa ziibhaktheriya ezine-gram-negative ezinganyangekiyo ngamayeza amaninzi kwaye kufuneka isetyenziswe ngobulumko ukugcina ukusebenza kwayo kunye nokunciphisa uphuhliso lokumelana okungakumbi. Ukunamathela kwimigaqo yokulawula iintsholongwane kubalulekile ekusebenziseni ngokufanelekileyo i-colistin sulfate ukuphucula iziphumo zezigulane nokuthintela ukusasazeka kweentlobo ezixhathisayo.