I-Cytochalasin B CAS:14930-96-2 Ixabiso lomenzi

I-Cytochalasin B yikhompawundi yendalo ephuma kwiintlobo ezahlukeneyo zefungi. Ikwiqela lekhompawundi eyaziwa ngokuba yi-cytochalasins, eyaziwa ngokuphazamisa i-cytoskeleton yeeseli.

Isiphumo esiphambili se-cytochalasin B kukuthintela i-actin polymerization. I-Actin yiproteni edlala indima ebalulekileyo ekugcineni imo yeseli kunye nokuhamba kwayo. Ngokuphazamisa i-actin, i-cytochalasin B iphazamisa iinkqubo ezahlukeneyo zeseli.

Enye yezona ndlela ziphambili zokusetyenziswa kwe-cytochalasin B kuphando lwebhayoloji yeseli. Isetyenziswa kakhulu njengesixhobo sokufunda i-actin dynamics kunye nendima yayo kwiinkqubo ezahlukeneyo zeseli, ezinje ngokwahlukana kweseli, ukuhamba kweseli, kunye ne-endocytosis. Ngokuthintela i-actin polymerization, i-cytochalasin B ivumela abaphandi ukuba baphande umsebenzi kunye nokubaluleka kwe-actin kwezi nkqubo.

Ngaphezu koko, i-cytochalasin B ibonakalise ukusetyenziswa kwayo okunokwenzeka kunyango. Ifundwe ngenxa yokukwazi kwayo ukuthintela ukukhula kweentlobo ezithile zeeseli zomhlaza, nto leyo ebonisa ukuba inamandla okulwa nomhlaza. Ukongeza, ibonakalise ukusebenza kwayo njengeyeza lokulwa nomhlaza kwiintsholongwane ezithile, nto leyo ebonisa ukuba inokusetyenziswa kunyango lokulwa nomhlaza.