I-D-fucose CAS: 3615-37-0 Ixabiso lomvelisi

I-D-fucose yi-monosaccharide, ngokukodwa iswekile yekhabhoni emithandathu, eyeqela leeswekile ezilula ezibizwa ngokuba yi-hexoses.Yi-isomer ye-glucose, eyahlukileyo kwi-configuration yeqela elinye le-hydroxyl.

I-D-fucose ifumaneka ngokwendalo kwizinto ezahlukeneyo, kubandakanya iibhaktheriya, umngundo, izityalo kunye nezilwanyana.Idlala indima ebalulekileyo kwiinkqubo ezininzi zebhayoloji, ezifana nokubonakaliswa kweeseli, ukunamathela kweeseli, kunye ne-glycoprotein synthesis.Iyingxenye ye-glycolipids, i-glycoproteins, kunye ne-proteoglycans, ebandakanyekayo kwi-cell-to-cell communication kunye nokuqaphela.

Kubantu, i-D-fucose iphinda ibandakanyeke kwi-biosynthesis yezakhiwo ezibalulekileyo ze-glycan, ezifana ne-Lewis antigens kunye ne-antigens yeqela legazi, ezineempembelelo ekusebenzisaneni kwegazi kunye nokuchaphazeleka kwezifo.

I-D-fucose inokufumaneka kwimithombo eyahlukeneyo, kubandakanywa ukhula lwaselwandle, izityalo, kunye nokuvutshelwa kwe-microbial.Isetyenziselwa uphando kunye nezicelo ze-biomedical, kunye nokuveliswa kwamachiza athile kunye neekhompawundi zonyango.

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Iimpembelelo ezichasene nokuvuvukala: I-D-fucose ibonakaliswe ukuba inezinto ezichasayo.Inokuthintela ukuveliswa kwe-cytokines e-pro-inflammatory kunye nokunciphisa ukusebenza kweeseli ze-immune, ngaloo ndlela zikwazi ukubonelela ngeenzuzo zonyango kwiimeko ezivuthayo.

I-Anticancer Effects: I-D-fucose ibonise imisebenzi ye-anticancer ngokuthintela ukwanda kweeseli zomhlaza, ukukhuthaza i-apoptosis (ukufa kweeseli), kunye nokucinezela ukukhula kwe-tumor.Iyakwazi ukumodareyitha ukubonakaliswa kofuzo olubandakanyekayo kulawulo lomjikelo weeseli kunye ne-metastasis.

I-Immunomodulatory Effects: I-D-fucose inokuchaphazela iimpendulo ze-immune ngokumodareyitha imisebenzi yeeseli zomzimba.Kuye kwaboniswa ukwandisa umsebenzi we-phagocytic we-macrophages, ukuvuselela ukuveliswa kwee-antibodies, kunye nokuphucula ukunxibelelana kweeseli zomzimba.

Iimpembelelo ze-Antibacterial: I-D-fucose ibonisa iipropati ze-antibacterial ezichasene neentlobo ze-pathogens.Inokuthintela ukunamathela kwebhaktheriya ekubambeni iiseli, ngaloo ndlela ikhusela ukubunjwa kwe-biofilm kunye nokunciphisa umngcipheko wosulelo lwebhaktheriya.

I-Glycosylation kunye ne-Glycosylation Inhibition: I-D-fucose idlala indima ebalulekileyo kwiinkqubo ze-glycosylation, ezibandakanya ukudibanisa kweeshukela kwiiprotheni okanye kwi-lipids.Ibandakanyeka kwi-biosynthesis ye-glycoproteins, i-glycolipids, kunye nezinye ii-carbohydrate eziyinkimbinkimbi.I-D-fucose analogs okanye inhibitors ingasetyenziselwa ukuphazamisa iinkqubo ze-glycosylation, ezinokuchaphazela imisebenzi yeselula kunye neemeko ze-pathological.

Izicelo zeBiomedical kunye noNyango: I-D-fucose kunye nezinto eziphuma kuyo zisetyenziswa kwizicelo ezahlukeneyo ze-biomedical kunye nezonyango.Zisetyenziswa njengezinto eziluhlaza kwimveliso yamayeza, ngakumbi amachiza okulwa neentsholongwane kunye ne-immunosuppressants.Iikhompawundi ezisekelwe kwi-D-fucose kunye ne-conjugates nazo zifundelwa amandla abo njengeenkqubo zokuhanjiswa kweziyobisi kunye nonyango olujoliswe kuyo.

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Iinkcukacha ezongezelelweyo:

Ukuqamba	C6H12O5
Isivavanyi	99%
Imbonakalo	Umgubo omhlophe
Inombolo yeCAS.	3615-37-0
Ukupakisha	Incinci kwaye ininzi
Beka ubomi kwishelufa	iminyaka eyi-2
Ugcino	Gcina kwindawo epholileyo neyomileyo
Isiqinisekiso	ISO.