I-D-SERINE CAS: 312-84-5

I-D-serine ifumene ingqwalasela enkulu ngenxa yezicelo zayo zonyango ezinokubakho, ngakumbi kwicandelo leengxaki zemithambo-luvo nezengqondo. Uphando lubonisa ukuba ukongezwa okanye ukuguqulwa kwamanqanaba ayo e-D-serine kunokuba nefuthe kwiimeko ezifana ne-schizophrenia, isifo sika-Alzheimer, kunye nokudakumba. Indima yayo ekulawuleni umsebenzi we-NMDA receptor iyibeka njengenjongo yophuhliso lwamayeza ajolise ekujongeni iingxaki zengqondo, ukuphazamiseka kwemood, kunye nezifo ze-neurodegenerative. Ngaphezu koko, ukubandakanyeka kwe-D-serine kwi-synaptic plasticity kunye neendlela ze-neuronal signaling kuxhasa ukubaluleka kwayo kuphononongo lomsebenzi wengqondo kunye nophuhliso lonyango lweemeko ze-neurological. Amandla ayo okuphucula umsebenzi we-NMDA receptor kunye nokukhuthaza i-neuroplasticity anika iindlela ezinokubakho zokungenelela ezijolise kwiimeko ezinxulumene ne-stroke, ukwenzakala kwengqondo okubuhlungu, kunye nezinye iingxaki ze-neurodegenerative. Ukongeza, ukusebenzisana kwe-D-serine neenkqubo ze-neurotransmitter kunye nempembelelo yayo kwi-neuronal excitability kukhokelele kuphando malunga nemiphumo yayo ekuguqulweni kwentlungu kunye nokukhusela i-neuroprotection, nto leyo ebonisa ukuba iluncedo kakhulu kulawulo lweentlungu kunye namaqhinga okukhusela i-neuroprotective ajolise kwiimeko ezinxulumene nomonakalo we-neuronal okanye ukungasebenzi kakuhle. Ngaphezu koko, i-D-serine inesithembiso kwicandelo lezonyango zokuvuselela kunye nobunjineli bezicubu, apho impembelelo yayo kwi-neurogenesis kunye nokuvuthwa kwe-neuronal inokunceda iindlela zokulungisa i-neural kunye nophuhliso lwezonyango zokwenzakala kwe-neurological kunye neengxaki zokuwohloka. Ngamafutshane, iindima ezininzi ze-D-serine kwi-neurophysiology, umsebenzi we-synaptic, kunye nempilo yengqondo ziyibeka njengemolekyuli enomdla kakhulu kwiindawo ezahlukeneyo zophando kunye nezicelo zeklinikhi, inikezela ngeendlela ezinokubakho zokungenelela konyango olujolise kwiimeko ze-neurological kunye ne-psychiatric, kunye negalelo ekuphuculeni ukuqonda kwethu umsebenzi wobuchopho kunye neengxaki ze-neurological.