I-Daptomycin CAS:103060-53-3

I-Daptomycin yi-antibiotic enamandla esetyenziswa kakhulu ekunyangeni izifo ezinzulu ezibangelwa yibhaktheriya eneGram-positive. Idla ngokugcinelwa iimeko apho ezinye ii-antibiotics ziye zasilela okanye azifanelekanga ngenxa yeendlela zokuxhathisa. Iimpawu eziqhelekileyo zokusetyenziswa kwe-daptomycin ziquka izifo ezintsonkothileyo zesikhumba kunye nezicubu ezithambileyo, ezifana ne-cellulitis, amathumba, kunye nosulelo lwamanxeba, kunye nosulelo lwegazi olufana ne-bacteremia kunye ne-infective endocarditis. Eli yeza linikwa ngemithambo yegazi phantsi kweliso leengcali zonyango esibhedlele. Umthamo kunye nobude bonyango bumiselwa bubukhali bosulelo, ubudala besigulana, ubunzima, kunye nokusebenza kwezintso. Kubalulekile ukulandela ishedyuli yedosi echazwe ngumniki-nkonzo wezempilo ukuqinisekisa iziphumo zonyango ezifanelekileyo kunye nokuthintela uphuhliso lokuxhathisa ii-antibiotic. Izigulana ezifumana i-daptomycin kufuneka zijongwe ngokusondeleyo naziphi na iimpawu zeziphumo ezimbi, kubandakanya iimpendulo ze-allergy, iintlungu zemisipha, okanye utshintsho kumsebenzi wezintso. Kubalulekile ukugqiba ikhosi epheleleyo yonyango njengoko kuyalelwe, nokuba iimpawu ziyaphucuka ngaphambi kokuba iyeza ligqitywe. Ukuqukumbela, i-daptomycin sisibulali-ntsholongwane esibalulekileyo ekunyangeni usulelo olukhulu lwebhaktheriya oluneGram-positive, olunika oogqirha isixhobo esisebenzayo sokulwa nosulelo olunzima nokuphucula iziphumo zezigulana kwiindawo zesibhedlele.