I-Evodia Rutaecarpa PE CAS: 2420-56-6 uMboneleli woMvelisi

I-Evodiamine inokunciphisa umsebenzi weendlela ezinxulumene ne-intracellular cyclic adenosine monophosphate (cAMP), ithintele umsebenzi we-3β-HSD kunye nezinye ii-enzymes ezinxulumene ne-steroid, inciphise kwaye ichaphazele ukudluliselwa kwesignali kunye nokubonakaliswa kwe-RNA activation Protein (StAR). Ingasebenza ngokuthe ngqo kwi-rat cortical adrenal cortex mesh cell ukuze kuthintelwe ukukhutshwa kwe-corticosterone. I-Evodiamine inokuthintela ukwanda kweeseli ezahlukeneyo ze-tumor, kubandakanya umhlaza wesibeleko, umhlaza wamathumbu amakhulu, umhlaza wamaphaphu, i-melanoma, i-T lymphocytic leukemia, umhlaza we-prostate kunye nomhlaza wamabele. Ukongeza, i-evodiamine inamandla amahle okubopha kwiiproteni ezahlukeneyo, ngoko ke ingasetyenziswa njenge-compound eneenjongo ezininzi ukudlala imisebenzi eyahlukeneyo yebhayoloji.