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I-Lasmiditant CAS:439239-90-4
I-Lasmiditan, ethengiswa phantsi kwegama lophawu iReyvow, yikhemikhali entsha yamayeza eyenzelwe ukunciphisa ukuhlaselwa yi-migraine ebukhali kubantu abadala. Ikwiqela le-agonists ye-receptor ye-serotonin ekhethiweyo, ejolise ngokukodwa kwi-5-HT1F receptor subtype. Le ndlela yokusebenza yahlula i-Lasmiditan kunyango lwe-migraine yendabuko, njengoko ingabangela ukuba i-vasoconstriction ingasebenzi, nto leyo eyenza ifaneleke kwizigulana ezineengxaki zentliziyo.
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I-N-Methylcarbonyl-2-chloroacetamidrazone CAS:155742-64-6
I-N-Methylcarbonyl-2-chloroacetamidrazone yikhemikhali eyaziwa ngokusetyenziswa kwayo ngeendlela ezahlukeneyo kwi-organic synthesis kunye ne-coordination chemistry. Ukwenziwa kwayo kubandakanya impendulo ye-N-methylcarbamoyl chloride ene-2-chloroacetohydrazide, nto leyo ebangela ukuba kubekho i-compound eneempawu ezahlukeneyo zesakhiwo kunye nokusebenza. Le compound ibonakaliswa kukwazi kwayo ukwenza ii-complexes ezinee-ion ezahlukeneyo zesinyithi, nto leyo eyenza ukuba ibe luncedo kwizifundo ze-coordination chemistry. Ukongeza, amaqela ayo e-carbonyl kunye ne-amidrazone anegalelo kwi-reactivity yayo kunye nemisebenzi enokubakho ye-pharmacological, eziziindawo ezinomdla wophando oluqhubekayo.
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I-Lasmiditan HCl CAS:613677-28-4
I-Lasmiditan hydrochloride (i-Lasmiditan HCl) yikhompawundi yamayeza eyaziwa ngendima yayo ekunyangeni ukuhlaselwa yi-migraine ebukhali kubantu abadala. Yaphuhliswa njenge-agonist ye-receptor ye-serotonin ekhethiweyo, ejolise ngokukodwa kwi-5-HT1F receptor subtype, i-Lasmiditan HCl imele inkqubela phambili ebalulekileyo kunyango lwe-migraine ngenxa yendlela yayo yokusebenza eyahlukileyo kunye nokusebenza kwayo kwezonyango.
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(6-aMinopyridin-2-yl)(1-Methylpiperidin-4-yl)Methanone CAS:613678-03-8
I-(6-Aminopyridin-2-yl)(1-methylpiperidin-4-yl)methanone, ekwaziwa ngokuba yi-aminopyridine methylpiperidone, yikhemikhali eneempembelelo ezibalulekileyo kwikhemistri yezonyango kunye nophando lweyeza. Le khompawundi yenziwe nge-reaction ye-6-aminopicolinic acid kunye ne-1-methylpiperidin-4-one, ibonisa iimpawu zesakhiwo ezahlukileyo ezinegalelo kwikhono layo lezonyango kunye nokusebenza ngokuguquguqukayo.
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(S)-(+)-3-Quinuclidinol CAS:34583-34-1
(S)-(+)-3-I-Quinuclidinol, eyaziwa ngokuba yi-quinuclidinol, yikhompawundi ebalulekileyo kwi-organic chemistry kunye nophando lweyeza ngenxa yokwahluka kwayo kwisakhiwo kunye nokusetyenziswa kwayo ngeendlela ezahlukeneyo. Le khompawundi ye-chiral ithathwe kwi-quinuclidine kwaye ibonisa iipropati ezahlukeneyo zeekhemikhali kunye neyeza eziye zatsala ingqalelo kwiinkalo ezahlukeneyo zesayensi.
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I-APREPITANT INTERMEDIATES CAS:171482-05-6
Ii-intermediates ze-Aprepitant zidlala indima ebalulekileyo ekuqulunqweni kwamayeza e-aprepitant, i-neurokinin-1 (NK1) receptor antagonist enamandla esetyenziswa kakhulu ekuthinteleni isicaphucaphu kunye nokuhlanza okubangelwa yi-chemotherapy (CINV). Ezi intermediates zizinto ezibalulekileyo kwindlela yokwenziwa enamanyathelo amaninzi ekhokelela ekuqulunqweni kokugqibela kwe-aprepitant. I-Aprepitant ngokwayo iyaziwa ngokusebenza kwayo ekulawuleni i-CINV, inika uncedo olukhulu kwizigulana ezisebenzisa i-chemotherapy. Ukwenziwa kwe-aprepitant kubandakanya amanyathelo aliqela abalulekileyo, kunye nee-intermediates ezisebenza njengeebhloko zokwakha ezivumela ukuveliswa ngokufanelekileyo kwale arhente yonyango ibalulekileyo.
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2,4,6-TRIFLUOROBENZOYL CHLORIDE CAS:79538-29-7
I-2,4,6-Trifluorobenzoyl chloride, ekwaziwa ngokuba yi-trifluorobenzoyl chloride, yikhemikhali ebalulekileyo exabisekileyo ngenxa yezicelo zayo ezahlukeneyo kwi-organic synthesis nakwiinkqubo zoshishino. Le compound, eyenziwe nge-chlorination ye-2,4,6-trifluorobenzoic acid, ibonisa iipropati ezahlukeneyo zeekhemikhali ezinegalelo ekusetyenzisweni kwayo ngokubanzi kwiindawo ezahlukeneyo.
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I-4-Chloro-6-iodoquinazoline CAS:98556-31-1
I-4-Chloro-6-iodoquinazoline yikhemikhali enefomula yemolekyuli i-C9H5ClIN2. Ibonakaliswa bubukho beeathom ze-chlorine kunye ne-iodine ezinamathele kwisakhiwo seringi ye-quinazoline. Le khompawundi isetyenziswa kakhulu kuphando lwamayeza kunye nokwenziwa kwezinto eziphilayo ngenxa yezicelo zayo ezinokubakho ekuphuhliseni amayeza amatsha kunye nezinye iimolekyuli ezisebenzayo kwibhayoloji.
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(R)-3-Quinuclinol CAS:25333-42-0
(R)-3-Quinuclinol, ekwaziwa ngokuba yiquinuclidinol, yinxalenye ebalulekileyo kwikhemistri yezinto eziphilayo kunye nophando lwezamayeza ngenxa yokwahluka kwayo kwisakhiwo kunye nokusetyenziswa kwayo ngeendlela ezahlukeneyo. Le nxalenye ye-chiral ithathwe kwi-quinuclidine kwaye ibonisa iimpawu ezahlukeneyo zeekhemikhali kunye nezamayeza eziye zatsala ingqalelo kwiinkalo ezahlukeneyo zesayensi.
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![(2R,3S)-2-[(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholine 4-methylbenzenesulfonate CAS:200000-59-5](https://cdn.globalso.com/xindaobiotech/8NS8DBIRAVXN0VCLT235.png)
(2R,3S)-2-[(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholine 4-methylbenzenesulfonate CAS:200000-59-5
I-compound (2R,3S)-2-[(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholine 4-methylbenzenesulfonate yimolekyuli yendalo entsonkothileyo eneempawu ezithile zesakhiwo kunye ne-pharmacological. Ikwiklasi yee-morpholine yee-compounds, ezihlala zisetyenziswa kwikhemistri yezonyango ngenxa yemisebenzi yazo eyahlukeneyo yebhayoloji.
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![(S)-3-Ethoxy-4-methoxy-α-[(methylsulfonyl)methyl]benzenemethanamine CAS:608141-42-0](https://cdn.globalso.com/xindaobiotech/1ZNB2ZF342ZWRNG304.png)
(S)-3-Ethoxy-4-methoxy-α-[(methylsulfonyl)methyl]benzenemethanamine CAS:608141-42-0
(S)-3-Ethoxy-4-methoxy-α-[(methylsulfonyl)methyl]benzenemethanamine yikhemikhali eyaziwayo ngokusetyenziswa kwayo okuguquguqukayo kwi-organic synthesis kunye ne-medical chemistry. Idityaniswe nge-reaction ye-(S)-1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethanone ene-ammonia okanye i-amine, le khemikhali ineempawu ezahlukeneyo zesakhiwo ezinegalelo kulwahlulo lwayo olusebenzayo kunye nemisebenzi enokubakho ye-pharmacological.
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(R)-1-(3-Ethoxy-4-Methoxyphenyl)-2-(Methylsulfonyl)ethylaI-CAS yeMine:608142-27-4
(R)-1-(3-Ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethylamine yikhemikhali eyaziwa ngezicelo zayo ezahlukeneyo kwi-organic synthesis kunye ne-medical chemistry. Idityaniswe nge-reaction ye-1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethanone ene-ammonia okanye i-amine, le khemikhali ibonisa iimpawu ezahlukeneyo zesakhiwo ezinegalelo ekusebenzeni kwayo okuguquguqukayo kunye nemisebenzi enokubakho ye-pharmacological.
