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I-Tetracycline CAS: 60-54-8
I-Tetracycline yi-antibiotic ebanzi ekwiklasi ye-tetracycline, ephuma kwi-chlortetracycline yendalo. Ithintela ukwenziwa kweproteni yebhaktheriya ngokubophelela kwi-ribosome yebhaktheriya, ngaloo ndlela ithintela ukunamathela kwe-aminoacyl-tRNA kwi-mRNA-ribosome complex. Le ndlela yokusebenza ikhokelela kwimiphumo yebhaktheriya ngokuchasene noluhlu olubanzi lweebhaktheriya ezinegram-positive kunye negram-negative, kunye ne-protozoa ethile.
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I-Teicoplanin CAS:61036-62-2
I-Teicoplanin yi-glycopeptide antibiotic ephuma kwi-Actinoplanes teichomyceticus, isebenza kakuhle kwiintsholongwane ezahlukeneyo zegram-positive kuquka i-methicillin-resistant Staphylococcus aureus (MRSA). Ithintela ukwenziwa kweeseli zebhaktheriya ngokuzibophelela kwi-D-alanyl-D-alanine terminus ye-peptidoglycan precursors, nto leyo ekhokelela kwi-cell lysis kunye nemiphumo ye-bactericidal. I-Teicoplanin idla ngokusetyenziswa kwiindawo zonyango ekunyangeni izifo ezinzulu ezibangelwa zizinto eziphilayo zegram-positive.
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I-Sulfisoxazol (4-amino-N-(3,4-dimethyl-5-isoxazolyl)benzenesulfonamide) I-CAS:127-69-5
I-Sulfisoxazole, ekwaziwa ngokuba yi-sulfafurazole, sisibulali-ntsholongwane se-sulfonamide esikwiklasi yeziyobisi ze-sulfa. I-sulfisoxazole echazwa njenge-4-amino-N-(3,4-dimethyl-5-isoxazolyl)benzenesulfonamide ngokwekhemikhali, ithintela ukukhula kweebhaktheriya ngokuphazamisa ukwenziwa kwe-folic acid. Le ndlela yokusebenza ijolise kwi-dihydropteroate synthase, i-enzyme ebalulekileyo kwimveliso ye-bacterial folate, ngaloo ndlela ithintela ukukhula nokwanda kwazo.
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I-Sulfapyridine CAS:144-83-2
I-Sulfapyridine yi-sulfonamide antibiotic eyayisetyenziswa kakhulu kunyango lwezifo ezibangelwa ziintsholongwane, ingakumbi ngexesha leMfazwe Yehlabathi yesiBini. Ikwiqela lamayeza e-sulfa, athintela ukukhula kweentsholongwane ngokuphazamisa ukwenziwa kwe-folic acid. I-Sulfapyridine inefuthe layo le-bacteriostatic ngokujolisa kwi-dihydropteroate synthase, i-enzyme ebalulekileyo kwimveliso ye-folate kwiintsholongwane.
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I-Tazobactam CAS:89786-04-9
I-Tazobactam sisithinteli se-beta-lactamase esinceda siphucule umsebenzi wee-antibiotics ze-beta-lactam ngokuzikhusela ekuwohlokeni zii-enzymes ze-beta-lactamase eziveliswa ziintsholongwane ezininzi ezimelana nezifo. Isetyenziswa rhoqo kunye nee-antibiotics ze-beta-lactam ezifana ne-piperacillin ukwandisa uluhlu lwazo lomsebenzi ngokuchasene neentlobo ngeentlobo zezifo zebhaktiriya. I-Tazobactam ibuyisela ngokufanelekileyo ukusebenza kwee-antibiotics ze-beta-lactam ngokuchasene neentsholongwane ezivelisa i-beta-lactamase, ngakumbi izinto eziphilayo ezine-gram-negative.
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I-Tigecycline CAS:220620-09-7
I-Tigecycline yi-antibiotic ye-glycylcycline ebanzi ethintela ukwenziwa kweproteni yebhaktheriya ngokubophelela kwi-30S ribosomal subunit, ngaloo ndlela inika iziphumo zebhaktheriya ezichasene noluhlu olubanzi lweebhaktheriya ezinegram-positive kunye negram-negative, kuquka neentsholongwane ezinganyangekiyo ngamayeza amaninzi. Inxulumene ngokwesakhiwo ne-tetracyclines kodwa inomsebenzi ophuculweyo ngokuchasene neentlobo ezinganyangekiyo ngenxa yendlela yayo eyahlukileyo yokusebenza kunye notshintsho lwesakhiwo.
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Ityuwa yesodium yeSulbactam CAS:69388-84-7
Ityuwa yesodium yeSulbactam sisithinteli se-beta-lactamase esisetyenziswa rhoqo kunye nee-antibiotics ezithile ukulwa nosulelo lweebhaktheriya. Isebenza ngokuthintela umsebenzi wee-enzymes ze-beta-lactamase eziveliswa ziibhaktheriya, nto leyo enokubangela ukuba ii-antibiotics zingasebenzi. Ngokuthintela ukonakala kwee-antibiotics ezifana neepenicillins kunye nee-cephalosporins, ityuwa yesodium yesulbactam inceda ukuphucula iipropati zazo zokulwa neebhaktheriya. Le khompawundi idla ngokusetyenziswa kunye nee-antibiotics ezifana ne-ampicillin ukudala iziphumo ezihambelanayo nxamnye noluhlu olubanzi lweebhaktheriya ezisengozini.
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I-Sulfadimidine CAS:57-68-1
I-Sulfadimidine, eyaziwa ngokuba yi-sulfamethazine, sisibulali-ntsholongwane se-sulfonamide esisetyenziswa kunyango lwezifo ezibangelwa ziintsholongwane. Ikwiklasi yemithi yokulwa neentsholongwane eyaziwa ngokuba zii-sulfa drugs, esebenza ngokuthintela ukukhula nokuzala kweentsholongwane. I-Sulfadimidine iphazamisa ukwenziwa kwe-folic acid kwiintsholongwane, into ebalulekileyo ekusindeni kwazo, nto leyo ekhokelela kwimiphumo ye-bacteriostatic ngokuchasene neentsholongwane ezahlukeneyo ze-gram-positive kunye ne-gram-negative.
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Ityuwa yesodium yeSulfacetamide CAS:6209-17-2
Ityuwa yesodium yeSulfacetamide sisiphumo esinyibilikayo emanzini se-sulfacetamide, i-antibiotic ye-sulfonamide esetyenziswa kakhulu kwi-compositions zangaphandle ukunyanga usulelo lwebhaktiriya lolusu namehlo. Olu hlobo lwetyuwa luphucula ukunyibilika kunye nokuzinza kwe-sulfacetamide, okwenza ukuba ifaneleke kwiindlela ezahlukeneyo zamayeza. Ityuwa yesodium yeSulfacetamide isebenza ngokuthintela ukukhula kweebhaktiriya, ngakumbi ezo zibangela iimeko ezifana ne-acne vulgaris, i-seborrheic dermatitis, kunye nosulelo lwamehlo olufana ne-conjunctivitis. Iphazamisa ukwenziwa kwe-bacterial folate, ijolise ngempumelelo kwiibhaktiriya ezininzi ezine-gram-positive kunye ne-gram-negative.
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I-Streptomycin sulfate CAS:3810-74-0
I-Streptomycin sulfate liyeza le-antibiotic elikwiklasi ye-aminoglycoside. Livela kwibhaktiriya iStreptomyces griseus kwaye lisetyenziswa kakhulu ukunyanga usulelo lwebhaktiriya. I-Streptomycin sulfate isebenza ngokuthintela ukwenziwa kweproteni yebhaktiriya, ngaloo ndlela ibulala ngempumelelo iibhaktiriya ezisengozini. Idla ngokumiselwa ukunyanga isifo sephepha, isifo sombefu, i-tularemia, kunye nezinye izifo ezibangelwa ziibhaktiriya ezisengozini. I-Streptomycin sulfate idla ngokufumaneka ngendlela yokutofa kwaye inikwa nge-intramuscular okanye nge-intravenous phantsi kweliso likagqirha.
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Ityuwa yesodium yeSulfamethoxazole CAS:4563-84-2
Ityuwa yesodium yeSulfamethoxazole sisiphumo esinyibilikayo emanzini se-sulfamethoxazole, i-antibiotic ye-sulfonamide esetyenziswa kunyango lwezifo zebhaktiriya. Olu hlobo lwetyuwa luphucula ukunyibilika kunye nokuzinza kwe-sulfamethoxazole, okwenza ukuba ifaneleke kwiifom ezahlukeneyo zamayeza. Ityuwa yesodium yeSulfamethoxazole inefuthe layo le-bacteriostatic ngokuthintela ukwenziwa kwe-folic acid kwiibhaktiriya, inkqubo ebalulekileyo ekukhuleni nasekuphindaphindeni kwazo. Isebenza kakuhle ngokuchasene noluhlu olubanzi lweebhaktiriya ezine-gram-positive kunye ne-gram-negative.
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I-Sulfamethoxazole CAS:723-46-6
I-Sulfamethoxazole yi-sulfonamide antibiotic esetyenziswa rhoqo xa idityaniswe ne-trimethoprim ukwenza iyeza elinamandla lokulwa neentsholongwane elaziwa ngokuba yi-co-trimoxazole okanye i-trimethoprim-sulfamethoxazole (TMP-SMX). Ikwiklasi ye-antimicrobials eyaziwa ngokuba yi-sulfa drugs, ethintela ukukhula kweentsholongwane ngokuphazamisa ukwenziwa kwe-folic acid. I-Sulfamethoxazole ijolise ngokukodwa kwi-dihydropteroate synthase, i-enzyme ebandakanyekayo kwimveliso ye-folate, ngaloo ndlela ivelisa iziphumo ze-bacteriostatic ngokuchasene noluhlu olubanzi lweentsholongwane ze-gram-positive kunye ne-gram-negative.
