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I-2-Hydroxyisonicotinic acid CAS:90-33-5
I-2-Hydroxyisonicotinic acid sisiphumo se-isonicotinic acid, esibonakaliswa bubukho beqela le-hydroxyl kwindawo yesibini yeringi ye-pyridine. Le khompawundi ibonisa imisebenzi eyahlukeneyo yebhayoloji, kubandakanya iipropati ezinokubakho zokulwa nokudumba. Ukufana kwayo nolwakhiwo nezinye izinto eziphuma kwi-nicotinic acid kwenza ukuba ibe yindawo enomdla yophuhliso lwamayeza. Abaphandi bebehlola ukusetyenziswa kwayo kwikhemistri yezonyango, ngakumbi kunyango lwezifo ezahlukeneyo. Le khompawundi isebenza njengebhloko yokwakha iimolekyuli ezintsonkothileyo kwaye ifumene ingqalelo kwicandelo lokwenziwa kwezinto eziphilayo kunye nophando lwamayeza.
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I-Methyl 2-aminopyridine-4-carboxylate CAS:6937-03-7
I-Methyl 2-aminopyridine-4-carboxylate yi-pyridine derivative eneqela le-amino kwindawo ye-2 kunye ne-carboxylate ester kwindawo ye-4, kunye neqela le-methyl eliqhotyoshelwe kwi-carboxylic acid. Le khompawundi inomdla kwikhemistri yezonyango ngenxa yemisebenzi yayo yebhayoloji, kubandakanya iipropati zokulwa nokubulala iintsholongwane kunye nokulwa nokuvuvukala. Ulungiselelo olulodwa lwamaqela asebenzayo luphucula ukusebenza kwayo kunye nokusebenza kwayo njengebhloko yokwakha eguquguqukayo kwi-organic synthesis. Uphando luyaqhubeka nokuhlola ukusetyenziswa kwayo kuphuhliso lwamayeza nakwezinye iinkalo, lubonisa ukubaluleka kwayo kwicandelo lekhemistri ye-heterocyclic.
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I-Tofacitinib Citrate CAS:540737-29-9
I-Tofacitinib citrate sisithinteli sikaJanus kinase (JAK) esisetyenziswa ngokuyintloko kunyango lwe-rheumatoid arthritis, i-psoriatic arthritis, kunye ne-ulcerative colitis. Isebenza ngokuthintela ngokukhetha ii-enzymes ze-JAK1 kunye ne-JAK3, ezidlala indima ebalulekileyo kwiindlela zokubonisa ii-cytokines ezahlukeneyo ezibandakanyeka kwiinkqubo zokudumba. Ngefomula yemolekyuli i-C16H20N6O5S·C6H8O7, i-tofacitinib citrate ibonakalise ukusebenza kakuhle ekunciphiseni ukudumba kunye nokuphucula umgangatho wobomi besigulana. Ivunyiwe ukuba isetyenziswe kwiklinikhi kumazwe aliqela, uphando oluqhubekayo lujolise ekuphononongeni usetyenziso lwayo olubanzi lonyango, iprofayili yokhuseleko, kunye neziphumo zexesha elide kwizifo ezahlukeneyo ze-autoimmune.
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I-Cyclen CAS: 294-90-6
I-Cyclen, okanye i-1,4,7,10-tetraazacyclododecane, yi-polyamine compound ephawulekayo ngesakhiwo sayo esijikelezayo esinee-athomu ezine ze-nitrogen ezifakwe kwisangqa esinamalungu alishumi elinesibini. Ngefomula ye-molecular C8H16N4, i-cyclen isebenza njenge-ligand ebalulekileyo kwi-coordination chemistry ngenxa yokukwazi kwayo ukwenza ii-complexes ezizinzileyo ngee-transition metals. Iimpawu zayo ze-chelating ziyenza ibe luncedo kwiindlela ezahlukeneyo zokusebenza, kubandakanya i-medicine chemistry, i-radiopharmaceuticals, kunye ne-supramolecular chemistry. Uphando oluqhubekayo luhlola amandla e-cyclen kwiinkqubo zokuhambisa amayeza kunye nophuhliso lwee-arhente ze-imaging ezijoliswe kuzo, zigxininisa ukubaluleka kwayo kwisayensi esisiseko kunye nesetyenziswayo.
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![I-4,4-dimethyl-3,5,8-trioxabicyclo[5.1.0]octane CAS:57280-22-5](https://cdn.globalso.com/xindaobiotech/8NS8DBIRAVXN0VCLT317.png)
I-4,4-dimethyl-3,5,8-trioxabicyclo[5.1.0]octane CAS:57280-22-5
I-4,4-Dimethyl-3,5,8-trioxabicyclo[5.1.0]octane yi-bicyclic organic compound ebonakaliswa yisakhiwo sayo esahlukileyo esiqulethe ii-ether linkages ezimbini kunye nee-athomu ezintathu ze-oxygen ngaphakathi kwesakhelo se-bicyclic. Ngefomula yemolekyuli i-C10H16O3, le compound ibonisa iipropati zeekhemikhali ezinomdla ngenxa yokubakho kwamaqela e-methyl kunye nemisebenzi ye-ether. Uyilo lwayo lwe-bicyclic lunegalelo ekuzinzeni nasekusebenzeni kwayo, okwenza ukuba ibe ngumviwa onokubakho kwizicelo ezahlukeneyo kwi-synthetic organic chemistry. Uphando luhlola ukusetyenziswa kwayo ekuhlanganiseni iimolekyuli ezintsonkothileyo kunye namandla ayo njengebhloko yokwakha kwisayensi yamayeza kunye nezinto eziphathekayo.
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![I-4-Chloro-7-[(4-methylphenyl)sulfonyl]-7H-pyrrolo[2,3-d]pyrimidine CAS:479633-63-1](https://cdn.globalso.com/xindaobiotech/VMLV8UWXAZ0XBLS6M290.png)
I-4-Chloro-7-[(4-methylphenyl)sulfonyl]-7H-pyrrolo[2,3-d]pyrimidine CAS:479633-63-1
I-4-Chloro-7-[(4-methylphenyl)sulfonyl]-7H-pyrrolo[2,3-d]pyrimidine yikhompawundi yokwenziwa ephawulekayo ngenxa yezicelo zayo ezinokubakho kwi-pharmacological. Inesakhiwo esahlukileyo esiquka isiseko se-pyrrolopyrimidine, indawo ye-chloro, kunye nenxalenye ye-sulfonyl edibene neqela le-para-methylphenyl. Olu lwakhiwo lunokuba negalelo kumsebenzi walo webhayoloji, nto leyo eyenza ukuba ibe ngumviwa wophando kwiindawo ezifana ne-oncology okanye ukudumba. Izifundo ziyaqhubeka ukuze kuhlolwe iindlela zayo zokusebenza, ukusebenza kakuhle, kunye neprofayili yokhuseleko, ngenjongo yokuchonga iindlela zayo ezinokubakho zonyango kwiimeko ezahlukeneyo zonyango.
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I-3-Pyridinesulfonyl chloride CAS:16133-25-8
I-3-Pyridinesulfonyl chloride yi-organic compound ebalulekileyo ene-molecular formula C6H6ClN O2S. Yi-sulfonyl chloride derivative ye-pyridine, eneqela elisebenzayo le-sulfonyl chloride eliqhotyoshelwe kwindawo yesithathu yeringi ye-pyridine. Le compound isetyenziswa kakhulu kwi-organic synthesis njenge-reagent yokungenisa amaqela e-sulfonyl kwi-substrates ezahlukeneyo. I-reactivity yayo ivumela ukuba ithathe inxaxheba kwi-nucleophilic substitution reactions, nto leyo eyenza ukuba ibe luncedo ekwakhiweni kwe-sulfonamides kunye nezinye ii-bioactive molecules. Ngaphezu koko, i-3-pyridinesulfonyl chloride inokusetyenziswa okunokwenzeka kwi-pharmaceuticals kunye ne-agrochemicals.
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I-2-Aminoisonicotinic acid CAS: 13362-28-2
I-2-Aminoisonicotinic acid yi-pyridine derivative, ingakumbi i-isomer ye-nicotinic acid, ebonakaliswa bubukho beqela le-amino kwindawo ye-2 yesakhiwo se-isonicotinic acid. Ngefomula yemolekyuli i-C6H6N2O2, le khompawundi ibonisa iipropati zeekhemikhali ezinomdla kwaye ifumene ingqalelo kwikhemistri yezonyango ngenxa yemisebenzi yayo yebhayoloji, kubandakanya nemiphumo yokulwa neentsholongwane kunye nokulwa nokuvuvukala. Imisebenzi ye-amino kunye ne-carboxylic acid ivumela ukuguqulwa kweekhemikhali ezahlukeneyo, okwenza ukuba ibe yindawo ephakathi ebalulekileyo kwi-organic synthesis. Uphando oluqhubekayo luhlola amandla ayo okunyanga, lugxininisa ukubaluleka kwayo kuphuhliso lwamayeza nakwezinye iindlela zokusebenza.
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I-2-Amino-4-cyanopyridine CAS:42182-27-4
I-2-Amino-4-cyanopyridine sisiphumo se-pyridine esibonakaliswa liqela le-amino kwindawo ye-2 kunye neqela le-cyano kwindawo ye-4 yeringi ye-pyridine. Ngefomula yemolekyuli i-C6H4N4, le khompawundi ibonisa iipropati zeekhemikhali ezinomdla kunye nemisebenzi enokubakho yebhayoloji. Ifundwe ngenxa yezicelo zayo kwikhemistri yezonyango, ngakumbi ekuphuhlisweni kwamayeza ngenxa yeziphumo zayo ezinokubakho zokulwa neentsholongwane, ukubola, kunye nokulwa nokuvuvukala. Ukubakho kwamaqela omabini asebenzayo kuphucula ukusabela kwayo, okwenza ukuba ibe yindawo ephakathi ebalulekileyo kwi-organic synthesis. Uphando luyaqhubeka nokuhlola ukuguquguquka kwayo kwiinkalo ezahlukeneyo kubandakanya amayeza kunye neekhemikhali zezolimo.
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I-2-(4-Hydroxyphenyl)-4-methyl-5-thiazolecarboxylic acid, i-ethyl ester, i-hydrochloride (1:1) I-CAS:399017-10-8
I-2-(4-Hydroxyphenyl)-4-methyl-5-thiazolecarboxylic acid, i-ethyl ester, i-hydrochloride (1:1) sisiphumo se-thiazole, esibonakaliswa bulwakhiwo lwayo olwahlukileyo oluquka iqela le-hydroxyl, iqela le-methyl, kunye ne-ethyl ester. Le khompawundi ifumene umdla kwi-chemistry yezonyango ngenxa yemisebenzi yayo yebhayoloji, njengeempawu zokulwa nokuvuvukala kunye ne-antimicrobial. Uhlobo lwetyuwa ye-hydrochloride luphucula ukunyibilika kunye nozinzo, okwenza kube lula ukusetyenziswa kwayo kwifomyula yamayeza. Uphando luyaqhubeka nokuphanda ukusebenza kwayo kwiindlela ezahlukeneyo zonyango, okwenza ukuba ibe ngumviwa obalulekileyo kwizifundo ezongezelelweyo kuphuhliso lwamayeza kunye nokwenza ngcono i-lead.
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I-3-Methyl-4-nitropyridine N-Oxide CAS:1074-98-2
I-3-Methyl-4-nitropyridine I-N-oxide sisithako se-pyridine esichazwa liqela le-methyl kwindawo ye-3 kunye neqela le-nitro kwindawo ye-4 yeringi ye-pyridine, kunye neqela elisebenzayo le-N-oxide. Le khompawundi ibonisa iipropati eziphawulekayo zeekhemikhali kunye nemisebenzi yebhayoloji, okwenza ukuba ibe nomdla kwiindawo ezahlukeneyo ezifana nekhemistri yamayeza kunye neekhemikhali zezolimo. Ubukho bamaqela e-nitro kunye ne-N-oxide bunokuphucula ukusebenza kwayo kunye nokusetyenziswa okunokwenzeka kwikhemistri yokwenziwa. Uphando luyaqhubeka nokuhlola ukusetyenziswa kwekhompawundi ekufumaneni amayeza nakwezinye izicelo, lubonisa ukubaluleka kwayo kwikhemistri yendalo yanamhlanje.
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(1R,2R)-N-Methylsulfonyl-1,2-diphenylethanediamine CAS:511534-44-4
(1R,2R)-N-Methylsulfonyl-1,2-diphenylethanediamine yikhompawundi ebalulekileyo ye-chiral eneqela elisebenzayo le-sulfonamide kunye nomqolo we-diphenylethylene. Ngefomula yemolekyuli i-C16H20N2O2S, le khompawundi idlala indima ebalulekileyo ekuhlanganiseni kunye ne-catalysis engalinganiyo ngenxa yokukwazi kwayo ukwenza iindawo ezizinzileyo ze-chiral. Ulwakhiwo lwayo olwahlukileyo luvumela iimpendulo ezikhethiweyo, nto leyo eyenza ukuba ibe luncedo kuphuhliso lwamayeza kunye neekhemikhali zezolimo. Uphando oluqhubekayo luhlola ukusetyenziswa kwayo ekuhlanganiseni i-stereoselective, lugxininisa amandla ayo njenge-ligand kwi-organometallic chemistry kwaye lwandisa ukubaluleka kwayo ekuhlanganiseni i-organic yanamhlanje.
