I-Fmoc-Glu(Kodwa)-NH2 CAS:104090-92-8

I-Fmoc-Glu(But)-NH2 isebenza njengesixhobo esiguquguqukayo kwi-peptide synthesis, inika abaphandi amandla okufaka i-glutamic acid ngolawulo oluchanekileyo kunye nokuguquguquka. Iqela elikhuselayo le-Fmoc likhusela iqela le-amino, liqinisekisa iimpendulo ezikhethiweyo ngexesha lokudibanisa i-peptide, ngelixa iqela le-butyl longeza umaleko owongezelelweyo wokhuseleko kwiqela le-carboxyl. Abaphandi basebenzisa kakhulu i-Fmoc-Glu(But)-NH2 ekwenzeni ii-peptides kwizicelo ezahlukeneyo, kubandakanya uyilo lwee-peptide mimetics, i-peptide conjugation, kunye nophuhliso lwee-peptides ezisebenzayo. Iqela le-amino livumela ukusebenza okungakumbi, okuvumela ukunamatheliswa kwee-molecules ezahlukeneyo, ii-fluorophores, okanye ezinye izinto ukuze zilungelelanise iipropati zee-peptides ezihlanganisiweyo. Ngaphezu koko, i-Fmoc-Glu(But)-NH2 ifumana uncedo kwizifundo ezinxulumene nophuhliso lwamayeza asekelwe kwi-peptide, njengoko iqela lokukhusela i-butyl liphucula uzinzo kunye nokukhululwa okulawulwayo kwe-glutamic acid efakiweyo. Ukuhambelana kwayo neendlela eziqhelekileyo zokwenziwa kwe-peptide, kuzo zombini izicwangciso zesigaba esiqinileyo kunye nesigaba sesisombululo, kuphucula ukuguquguquka kwayo kwimisebenzi eyahlukeneyo yophando. Ngamafutshane, i-Fmoc-Glu(But)-NH2 imele njengesixhobo esisisiseko nesingenamsebenzi kwikhemistri yepeptide, inika abaphandi ibhloko yokwakha eguquguqukayo yokwenza iipeptides ezenzelwe wena kunye nemisebenzi ethile, ngakumbi igxile kwiipeptides eziqulethe i-glutamic acid.