I-Fmoc-MeIle-OH CAS:138775-22-1

I-Fmoc-MeIle-OH ifumana ukusetyenziswa okubanzi kwi-peptide chemistry, uphando lwamayeza, kunye ne-biotechnology ekudaleni iipeptides ezinezakhiwo kunye neempawu eziguquliweyo. Njengenxalenye esisiseko kwi-solid-phase peptide synthesis, ivumela ukwakhiwa kweepeptides ngotshintsho oluthile lwe-sequence, ivumela abaphandi ukuba baphande impembelelo ye-N-methylation kwi-peptide conformation, uzinzo, kunye ne-bioactivity. I-Fmoc-MeIle-OH isetyenziswa ekuphuhlisweni kwee-peptide analogs, ii-peptidomimetics, kunye nezifundo zobudlelwane besakhiwo-umsebenzi ezigxile ekuphuculeni abaviwa beziyobisi ezisekelwe kwi-peptide. Ubunyulu obuphezulu kunye nokuzinza kwe-Fmoc-MeIle-OH kwenza kube lukhetho olufanelekileyo lokuvelisa iipeptides ngolawulo oluchanekileyo kwi-N-methyl isoleucine incorporation. Ukuhambelana kwayo nemigaqo eqhelekileyo yokwenziwa kwe-peptide kunye nee-reagents kuqinisekisa ukuhlanganiswa okungenamthungo kwimisebenzi yelabhoratri, inika amandla izazinzulu ukuba zenze iipeptides ngezakhiwo kunye nemisebenzi eyenzelwe zona. Nokuba isetyenziswa kuphando lwezemfundo okanye kwizicelo zoshishino, i-Fmoc-MeIle-OH inegalelo ekuphuculeni icandelo lokufunyanwa kwamayeza asekelwe kwi-peptide, uphando lwezonyango, kunye nophuhliso lwezonyango ezintsha ze-peptide kwizicelo ezahlukeneyo zonyango.