I-H-Asp-(OBzl)-OBzl·TOS CAS:2886-33-1

I-H-Asp-(OBzl)-OBzl·Tos idlala indima ebalulekileyo ekwenziweni kwe-peptide, apho amaqela akhusela i-benzyl ester kunye nokusebenza kwe-tosyl kunceda ukuthintela iimpendulo ezingafunekiyo ngexesha lokuhlanganiswa kwee-peptides eziqulethe ii-aspartic acid residues. Oku kwenza kube lula ukulungiselela ii-peptides eziguquliweyo zokufunda ukusebenzisana kweproteni-protein, ubudlelwane be-enzyme-substrate, kunye nokuhambelana kwesakhiwo-umsebenzi. Ngaphezu koko, le compound ifumana isicelo ekwenziweni kwe-solid-phase peptide, indlela esisiseko kwi-peptide chemistry kunye nemizamo yokufumanisa iziyobisi, evumela uphuhliso lwee-peptides ezintsha kunye nee-peptidomimetics ezinezicelo zonyango ezinokubakho. Ngaphezu koko, i-H-Asp-(OBzl)-OBzl·Tos inegalelo ekuphuculeni ukuqonda kwethu ubudlelwane besakhiwo-umsebenzi we-peptide kwaye isebenza njengecandelo elibalulekileyo ekuphononongweni kweempawu ezahlukeneyo zesayensi ye-peptide. Uncedo lwayo lufikelela kuphando kwi-bioconjugation kunye ne-chemical biology, oluququzelela ukuhlanganiswa kwee-peptides kwezinye iimolekyuli ukuze kunikezelwe okanye kuxilongwe ngendlela ekujoliswe kuyo. Lilonke, isebenza njengesixhobo esibalulekileyo, esenza abaphandi bakwazi ukuphonononga ubunzima be-peptide chemistry kunye neziphumo zayo kuphando lwezonyango, uphuhliso lwamayeza, kunye nokungenelela okunokwenzeka konyango. Ngezicelo zayo ezibanzi kuphando lwe-peptide, le reagent ixabisa kakhulu ekuphuculeni ulwazi lwesayensi kunye negalelo kuphuhliso lwezonyango ezisekelwe kwi-peptide.