I-H-Glu-OBzl CAS:13030-09-6

I-H-Glu-OBzl isebenza njengebhloko ebalulekileyo ekwakheni i-peptide, evumela ukuguqulwa kweentsalela ze-glutamic acid ngaphakathi kwee-peptides. Ukusebenza kwe-benzyl ester kwenza kube lula ukulawula ukulawulwa kweetyathanga ze-glutamic acid, okuvumela ukulungiswa kwee-peptides eziguquliweyo zokuphanda ukusebenzisana kweproteni-protein, ukubopha kwe-receptor-ligand, kunye nobudlelwane bolwakhiwo nomsebenzi. Ukongeza, le compound ifumana isicelo kwi-solid-phase peptide synthesis, inegalelo ekuvelisweni kwee-peptides ezintsha ezineempawu ezilungiselelweyo kunye nezicelo zonyango ezinokubakho. Ngaphezu koko, i-H-Glu-OBzl ixhasa uphando olujolise ekuqondeni indima ye-glutamic acid kwiinkqubo zebhayoloji kunye nophuhliso lwamayeza. Ivumela izazinzulu ukuba zihlole impembelelo yeentsalela ze-glutamic acid eziguquliweyo kwisakhiwo kunye nomsebenzi we-peptide, inegalelo ekuphuculeni unyango olusekelwe kwi-peptide kunye nokufunyanwa kwamayeza. Uncedo lwayo lufikelela kuphando kwi-enzymology, i-neurobiology, kunye nesayensi yezinto, inika ulwazi oluxabisekileyo malunga nokuguquguquka kwee-peptides eziqulethe iintsalela ze-glutamic acid eziguquliweyo. Lilonke, i-H-Glu-OBzl imele njengesixhobo esibalulekileyo, inika amandla abaphandi ukuba bahlolisise ubunzima be-peptide chemistry kunye neziphumo zayo kuphando lwezonyango kunye nokungenelela konyango. Ngezicelo zayo ezibanzi kuphando lwe-peptide, le reagent inexabiso elikhulu ekuphuculeni ulwazi lwesayensi kunye negalelo kuphuhliso lwamayeza kunye nezixhobo ezisekelwe kwi-peptide.