I-H-MeAla-OH CAS:3913-67-5

I-H-MeAla-OH idlala indima ebalulekileyo ekuhlanganisweni nasekuguqulweni kwe-peptide ngenxa yokuba ikwazi ukungenisa iinxalenye ze-N-methyl-L-alanine kwizakhiwo ze-peptide. Olu tshintsho luvumela abaphandi ukuba bafunde kwaye batshintshe iipropati ze-peptides kunye neeproteni, nto leyo evumela ukuqhubela phambili ekufumaneni amayeza kunye nophando lweenkqubo zebhayoloji. Kuphuhliso lwamayeza, i-H-MeAla-OH isetyenziswa ekuvelisweni kwamayeza asekelwe kwi-peptide kunye ne-bioconjugates. Ukusebenza kwayo kunye nokucaciswa kwayo kuvumela ukuphathwa ngokuchanekileyo kwezakhiwo ze-peptide, okufaka isandla kuyilo lweearhente zonyango ezintsha kunye nokungenelela okujoliswe kuko. Ngaphezu koko, kuphando lwe-biochemical, i-H-MeAla-OH ivumela izazinzulu ukuba zihlolisise kwaye zilawule imisebenzi kunye nokusebenzisana kwee-peptides kunye neeproteni. Ukusetyenziswa kwayo ekuguquleni ulandelelwano lwe-peptide kunokukhokelela ekuqondeni iindlela ze-molecular kunye neenjongo ezinokubakho zophuhliso lwamayeza, ngaloo ndlela inegalelo ekuqondeni ngokubanzi iinkqubo zebhayoloji. Xa usebenza ne-H-MeAla-OH, ukunamathela kwimigaqo yokhuseleko lwelabhoratri esekwe kunye nezikhokelo zokuphatha kubalulekile ukuqinisekisa ukusetyenziswa ngokufanelekileyo kunye nokunciphisa iingozi ezinxulumene nee-reagents zamakhemikhali. Ukuqonda indlela ethile yokusabela kunye nokusetyenziswa kwe-H-MeAla-OH ngaphakathi komxholo wokwenziwa kunye nokuguqulwa kwe-peptide kubalulekile ekwenzeni iimvavanyo eziphumelelayo kunye nokufezekisa iziphumo zesayensi ezinqwenelekayo.