I-H-MeIle-OH CAS:4125-98-8

I-H-MeIle-OH idlala indima ebalulekileyo ekuqulunqweni kwe-peptide, isebenza njengebhloko ebalulekileyo yokwakha ii-peptides ezineempawu ezithile zesakhiwo kunye nokusebenza. Ubukho beqela le-methyl buchaphazela ukusebenza kweekhemikhali kunye nokusebenzisana kwe-hydrophobic kwe-peptide, okwenza ibe luncedo ekuyileni ii-peptides ezinokwandiswa kokungena kwe-membrane okanye izakhono ezithile zokujolisa. Ekuphuhlisweni kwamayeza, le khompawundi ingasetyenziselwa ukwenza amayeza asekelwe kwi-peptide anozinzo oluphuculweyo kunye nokufumaneka kwezinto eziphilayo, okunokukhokelela ekusebenzeni ngcono konyango. Ngaphezu koko, kuphando lwe-proteomics kunye ne-biochemical, i-H-MeIle-OH ifumana isicelo ekufundeni ukusebenzisana kweproteni-protein, ukuphanda imisebenzi ye-enzyme, kunye nokuphonononga iindlela zokubonisa iiseli. Iimpawu zayo ezikhethekileyo zivumela abaphandi ukuba baphonononge ubunzima beenkqubo zeseli kunye neendlela zesifo, zinegalelo ekuphuculeni ukuqonda impilo kunye ne-pathology. Ukuguquguquka kunye nokuhambelana kwekhompawundi neemeko ezahlukeneyo zovavanyo kwenza ukuba ibe yinxalenye ebalulekileyo yokutyhila ubunzima beenkqubo zebhayoloji kunye nokuphuhlisa iindlela zokungenelela ezijolise kuzo kwiimeko ezahlukeneyo zonyango. Ngamafutshane, i-H-MeIle-OH imele isixhobo esibalulekileyo kubaphandi kwi-peptide synthesis, uphuhliso lwamayeza, kunye nezifundo ze-biochemical, enika amandla okulungisa iipeptides ezineempawu ezithile kunye nokusombulula iindlela ezisisiseko zeenkqubo zebhayoloji, ngaloo ndlela inegalelo ekuphuculeni amayeza kunye ne-biotechnology.