IHygromycin B CAS:31282-04-9 Ixabiso lomenzi

I-Hygromycin B yi-antibiotic ephuma kwi-bacterium Streptomyces hygroscopicus. Isebenzisa iziphumo zayo ngokuthintela ukwenziwa kweproteni kwiiseli ngokuphazamisa umsebenzi we-peptidyl transferase we-ribosome. I-Hygromycin B isebenza kakuhle ngokuchasene neentlobo ezahlukeneyo zeebhaktheriya, iifungi, kunye neeseli eziphezulu ze-eukaryotic.

Enye indlela esetyenziswa kakhulu yiHygromycin B kukukhetha izinto kwi-molecular biology kunye novavanyo lobunjineli be-genetic. Isetyenziswa kakhulu njengophawu olukhethiweyo kwimveliso yezinto eziphilayo eziguqulweyo, ezifana nezityalo, izilwanyana kunye neebhaktheriya. Ngokuzisa ukumelana ne-gene encoding resistance kwiHygromycin B, abaphandi banokuchonga ngokulula kwaye bakhethe iiseli okanye izinto eziphilayo eziye zafaka ngempumelelo utshintsho lwe-genetic olufunekayo.

Ukuze kusetyenziswe iHygromycin B ekukhetheni, iiseli okanye izinto eziphilayo zihlala zinyangwa nge-antibiotic. Ziiseli eziye zadibanisa ngempumelelo i-resistance gene kuphela ezinokuphila zize ziqhubeke zikhula, ngelixa iiseli ezingatshintshwanga zifa. Oku kuvumela abaphandi ukuba bahlukanise kwaye basasaze iiseli ezifunekayo eziguqulwe ngokwemfuza ukuze zihlalutywe okanye zisetyenziswe ngakumbi.

Ukongeza ekusetyenzisweni kwayo kubunjineli bemfuza, iHygromycin B ikwasetyenziswa njengearhente yokulwa neentsholongwane kunye nokubola kwiindawo ezahlukeneyo zophando. Isetyenziswa kwiinkqubo zokukhulisa iiseli ukuthintela ungcoliseko ziibhaktheriya, iifungi, kunye nezinye iintsholongwane ezinokuphazamisa ukukhula kunye nokufunda kweeseli.