I-Losartan Potassium CAS: 124750-99-8 Umthengisi woMvelisi

I-Losartan potassium yeyona arhente yokuqala enamandla nekhethayo ye-AT1 receptor antagonist engeyiyo i-peptide engeniswa kwimarike njengeyeza lokulwa noxinzelelo lwegazi elithathwa kanye ngemini. Iyasebenza kwaye ihlala ixesha elide ekulawuleni uxinzelelo lwegazi kwiimpuku ezine-hypertension ezizenzekelayo, kwizigulane ezine-essential hypertension ukongeza kwizigulane ezine-renal disorder. Ngaphandle koko, uphando lwakutshanje lubonise ukuba i-losartan iluncedo ekubuyiseleni ukungasebenzi kakuhle okunxulumene nobudala ekugcineni uxinzelelo lwegazi oluqhelekileyo kunye nokusetyenziswa kwamandla eeseli kwi-mitochondria kwaye isenokusetyenziselwa ukunyanga i-left ventricular hypertrophy. Ingasetyenziswa njengenye indlela yokunyanga ukungasebenzi kakuhle kwe-systolic, i-myocardial infarction, isifo se-coronary artery, kunye nokusilela kwentliziyo.