I-N-Acetyl-D-proline CAS:59785-68-1

I-N-Acetyl-D-proline ibaluleke kakhulu kwi-peptide chemistry njengeyona nto iphambili ekuhlanganisweni kwee-peptides kunye nee-peptidomimetics. Njenge-acetylated D-proline derivative, isebenza njenge-intermediate eguquguqukayo yokungenisa ii-chiral residues ezithile kwii-peptide chains ngeendlela zokwenziwa kwe-peptide yesigaba esiqinileyo kunye nesigaba sesisombululo. Abaphandi kunye neengcali zekhemistri basebenzisa i-N-Acetyl-D-proline ukwenza ngokwezifiso ulandelelwano lwe-peptide ngolawulo oluchanekileyo lwe-stereochemical, okuvumela uyilo lwee-compounds ezintsha ze-bioactive kunye nee-peptides zonyango ezijolise kwii-receptors, ii-enzymes, okanye abathuthi kwiinkqubo zebhayoloji. Ngaphezu koko, i-N-Acetyl-D-proline isetyenziswa njengebhloko yokwakha i-chiral ekuvelisweni kwee-pharmaceutical intermediates, apho i-stereochemistry yayo eyahlukileyo ibalulekile ekuhlanganisweni kwamayeza e-chiral kunye nee-bioactive compounds. I-chirality yayo kunye nokuzinza kwayo kuyenza ibe yinto ebalulekileyo ekuvelisweni kweemveliso zamayeza, ukuphucula iipropati ze-pharmacological kunye nomsebenzi webhayoloji wamayeza okugqibela. Ngaphezu koko, i-N-Acetyl-D-proline isetyenziswa kuphando lwe-biochemical ukufunda i-proline metabolism, umsebenzi weproteni, kunye ne-enzyme kinetics. Indima yayo ekucaciseni iindlela zeeseli kunye neenkqubo ze-metabolic inegalelo ekuqondeni imisebenzi ye-proline kwiinkqubo zebhayoloji kunye nefuthe layo elinokubakho kwimpilo nakwizifo. Ngamafutshane, i-N-Acetyl-D-proline idlala indima ebalulekileyo ekuphuculeni uphando lwesayensi, uphuhliso lwamayeza, kunye nezifundo ze-biochemical, inika izazinzulu kunye neengcali isixhobo esiguquguqukayo sokuhlola ukusetyenziswa okwahlukeneyo kwe-proline derivatives ekufumaneni amayeza, ukwenziwa kwe-peptide, kunye nophando lwe-biochemical.