N,N'-Disuccinimidylcarbonate CAS:74124-79-1

I-N,N'-Disuccinimidylcarbonate idlala indima ebalulekileyo kwi-bioconjugation nakwi-biochemistry, isebenza njengecandelo eliphambili ekusebenzeni kweeproteni, iipeptides, ii-antibodies, kunye nezinye iimolekyuli zebhayoloji. Ukusebenza kwayo kumaqela e-amine kwenza ukwakheka konxibelelwano oluzinzileyo lwe-covalent, okwenza kube lula ukudibanisa ii-biomolecules kwiindawo eziphezulu, iipolymers, kunye nee-nanoparticles kwiinjongo ezahlukeneyo ze-biotechnology kunye nezonyango. Ukongeza, le compound isetyenziswa kakhulu ekuhlanganiseni iiprodrugs kunye neenkqubo zokuhambisa amayeza, apho isebenza njengekhonkco elixabisekileyo lokudibanisa iiarhente zonyango kwiimolekyuli ezijolise kuzo okanye amaqonga okuthwala. Ngokuvumela ulawulo oluchanekileyo malunga nokuncamathiselwa kweekhompawundi ze-bioactive, i-N,N'-Disuccinimidylcarbonate inegalelo kuphuhliso lwezonyango ezijoliswe kuzo kunye namaqhinga okuhambisa amayeza asebenzayo kunye neeprofayili ze-pharmacokinetic eziphuculweyo. Ngaphezu koko, i-N,N'-Disuccinimidylcarbonate ifumana ukusetyenziswa ekwenziweni kwezinto ze-biomaterials, ii-hydrogels, kunye nee-biosensors ngokwenza kube lula ukuthintela ii-biomolecules kwizibonelelo eziqinileyo kunye neendawo ezisebenzayo. Indima yayo ekudaleni ii-interfaces ze-bioactive kunye nezixhobo ezilungiselelwe yona iphucula ukusebenza kunye nokusebenza kwezixhobo ze-biomedical, izixhobo zokuxilonga, kunye nokwakhiwa kobunjineli bezicubu. Ngaphezu koko, le khompawundi ibalulekile ekuvelisweni kwee-molecular probes kunye nee-imaging agents ezisetyenziswa kwiindlela ze-biomedical imaging ezifana ne-positron emission tomography (PET) kunye ne-fluorescence microscopy. Ukusetyenziswa kwayo ekulebheleni ii-biomolecules ngamaqela eentatheli kuvumela ukubonakala kunye nokulandelela iithagethi ezithile zebhayoloji, okufaka isandla ekuqhubekeni kokuxilongwa kwesifo kunye nophando olusisiseko lwebhayoloji. Ngokubanzi, i-N,N'-Disuccinimidylcarbonate imi njengesixhobo esiguquguqukayo nesibalulekileyo kwimimandla ye-bioconjugation, i-chemical biology, kunye nobunjineli be-biomedical, idlala indima ebalulekileyo ekuphuhlisweni kwezixhobo ezintsha kunye netekhnoloji enezicelo ezibanzi kwi-carecare kunye ne-life sciences.