Novobiocin sodium ityuwa CAS: 1476-53-5

Kwi-microbiology, ityuwa yesodium ye-novobiocin isetyenziswa kwiimvavanyo ezahlukeneyo zokuxilonga, ezifana novavanyo lwe-novobiocin susceptibility test ukuze kwahlulwe phakathi kwe-coagulase-positive kunye ne-coagulase-negative staphylococci. Olu vavanyo lubandakanya ukugonyela i-bacterial isolate kwiiplate ze-agar ezongezelelwe yi-novobiocin kunye nokujonga indawo yokuthintela ukukhula ejikeleze idiski ye-antibiotic. I-Coagulase-positive staphylococci, kuquka ne-Staphylococcus aureus, zihlala zixhathisa kwi-novobiocin, ngelixa i-coagulase-negative staphylococci zichaphazeleka. Ukongeza, i-novobiocin isetyenziswa kwiindawo zophando ukuze ifunde i-bacterial DNA gyrase inhibition, iindlela zokumelana ne-antibiotic, kunye nokusebenzisana kwamayeza. Isebenza njengesixhobo se-pharmacological sokuphanda i-physiology yebhaktiriya, i-genetics, kunye ne-pathogenesis, inegalelo ekuqondeni iindlela zokumelana ne-antibiotic kunye nophuhliso lweendlela ezintsha zonyango. Ngaphandle kokusetyenziswa kwayo kwi-microbiology kunye nophando, i-novobiocin inezicelo ezimbalwa zeklinikhi ngenxa yobuthi bayo kunye nokufumaneka kwezinye iindlela ezikhuselekileyo. Nangona kunjalo, isaqhubeka iyinxalenye ebalulekileyo kwimisebenzi yelabhoratri yokuchonga iintsholongwane kunye novavanyo lokuchaphazeleka ziintsholongwane, ixhasa ukuxilongwa ngokuchanekileyo kunye nonyango olusebenzayo losulelo lweentsholongwane. Ukuphathwa, ukugcinwa, kunye nokulahla ityuwa yesodium ye-novobiocin ngokufanelekileyo kuyimfuneko ukuqinisekisa ukhuseleko lwelabhoratri kunye nokukhuselwa kwendalo, ngokuhambelana neenkqubo ezimiselweyo kunye nezikhokelo zomthetho.