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I-Dapagliflozin Propanediol CAS: 461432-26-8
I-Dapagliflozin Propanediol, i-sodium glucose cotransporter 2 inhibitor, luhlobo olutsha lweziyobisi ezichasene nesifo seswekile;Ingasetyenziswa njengokhetho olubalulekileyo kunyango lweziyobisi lwesifo sikashukela, kwaye lunokusetyenziswa njengesondlo esincedisayo kunye nokuzivocavoca ukuphucula ulawulo lweswekile yegazi kubantu abadala abane-2 yeswekile.
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I-Leflunomide CAS: 75706-12-6 uMboneleli woMvelisi
I-Leflunomide sisiyobisi se-antirheumatic esifumaneka ngomlomo kwaye yasungulwa njenge-Arava e-US kunyango lwe-rheumatoid arthritis (RA);liyeza lokuqala kunye nekuphela kweyeza eliya kuboniswa ukuba licothise umonakalo odibeneyo wesakhiwo se-RA, ngoko ke ukujongana nesidingo sonyango esingafezekiyo.I-Leflunomide yi-pro-drug ekhawulezayo kwaye iphantse isetyenziswe ngokupheleleyo kwi-metabolized (isiqingatha sobomi,
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Tofacitinib CAS:477600-75-2 uMboneleli woMvelisi
I-Tofacitinib yi-molecule yokuqala encinci ye-kinase inhibitor evunyiweyo kunyango lwe-RA.I-Tofacitinib iyi-inhibitor ye-subtypes ezine ze-Janus kinase (JAK): i-JAK1, i-JAK2, i-JAK3, kunye ne-Tyk2.Izenzo ze-Tofacitinib ngokuvimbela i-phosphorylation kunye nokusebenza kwe-transducers yesignali kunye ne-activators of transcription (STATs), ngaloo ndlela icinezela abalamli abavuthayo. kwizicubu ezidibeneyo.
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I-Aspartic Acid CAS: 56-84-8 uMboneleli woMvelisi
Aspartic Acidisetyenziswa njengesongezelelo sokutya, inokudityaniswa neeminerali ukwenza iikhompawundi ezifana ne-potassium aspartate, i-copper aspartate, i-manganese aspartate, i-magnesium aspartate, i-zinc aspartate kunye nokunye.Ukonyusa ukufunxwa, kunye nokusetyenziswa okunokwenzeka, kwezi zimbiwa ngokongezwa kweaspartate kubangela izibonelelo ezithile zempilo.Iimbaleki ezininzi zisebenzisa izongezelelo zeminerali ezisekwe kwi-L-aspartic acid ngomlomo ukukhulisa amandla abo okusebenza.I-Aspartic acid kunye ne-glutamic acid idlala indima ebalulekileyo njenge-asidi ngokubanzi kumaziko asebenzayo e-enzyme, kunye nokugcina i-solubility kunye ne-ionic character of proteins.
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I-Cetilistat CAS: 282526-98-1 uMboneleli woMvelisi
I-Cetilistat luhlobo olutsha lwe-pancrelipase inhibitor kunyango lokutyeba kakhulu kwi-diabetic kunye ne-non-diabetic, i-gastrointestinal lipase inhibitor esebenza ixesha elide, edlala umphumo wonyango ngokwenza i-covalent bond kunye ne-serine site esebenzayo ye-gastric lipase. kunye ne-pancreatic lipase esiswini kunye namathumbu amancinci ukuze angasebenzi i-enzyme.I-enzymes ye-Living Chemicalbook ayikwazi ukwenza i-hydrolyze amanqatha ekutyeni, ngakumbi i-triglycerides ibe yi-acids efunxayo yasimahla kunye ne-monoacylglycerols.I-triglycerides engaxutywanga ayinakuthatyathwa ngumzimba, ngaloo ndlela inciphisa i-caloric intake kunye nokulawula ubunzima.
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I-Paroxetine HCL CAS: 78246-49-8 uMboneleli woMvelisi
I-Paroxetine hydrochloride yityuwa ye-hydrochloride ye-paroxetine.Lichiza lokuthomalalisa uxinzelelo.Inendima njenge-antidepressant, i-anxiolytic drug, i-hepatotoxic agent, i-P450 inhibitor kunye ne-serotonin uptake inhibitor.Iqulethe i-paroxetinium (1+).
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I-Famotidine CAS: 76824-35-6
I-Famotidine ngumchasi we-histamine H2-receptor, okhuthaza ukuphiliswa kwe-erosive esophagitis, izilonda zesisu kunye ne-duodenal kuba inqanda ukukhutshwa kwe-asidi yesisu ebantwini.It isetyenziselwa unyango kunye nokuthintela izilonda ezenzeka esiswini kunye namathumbu.Iyakwazi ukunyanga izifo ezifana neZollinger-Ellison syndrome apho isisu siqokelela ubuninzi beeasidi.Ngaphezu koko, isetyenziswe ngexesha lokunyanga isifo se-reflux ye-gastroesophageal (GERD) kunye neemeko ze-pathological hypersecretory.
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I-Rivaroxaban CAS: 366789-02-8 uMboneleli woMvelisi
I-Rivaroxaban i-agent ye-antithrombotic inoveli.Yinoveli, ngomlomo, inhibitor ekhethiweyo ethe ngqo ye-factor Xa ephuhliswe yi-Bayer Healthcare.Ivunyiwe yi-EMEA kunye ne-FDA yokuthintela i-thromboembolism eyingozi kwizigulane zabantu abadala emva kokutshintshwa kwe-hip epheleleyo okanye utyando olupheleleyo lokuguqa.
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I-Glutamine CAS: 56-85-9 uMboneleli woMvelisi
I-Glutamine yi-alpha-amino acid enye ye-20 amino acids equkethe iiprotheni.I-L-glutamine yi-amino acids engabalulekanga kwaye ikwayeyona ininzi kakhulu kwimizimba yabantu.Ibandakanyeka kwiinkqubo ezininzi zebhayoloji ezibalulekileyo.Ngokomzekelo, yibhloko yokwakha iprotheni synthesis njengenye i-amino acid ephambili;isetyenziswe kwi-biosynthesis ye-urea kunye ne-purines ye-nucleic acid synthesis;yi-substrate ye-biosynthesis ye-neurotransmitters;ikwayimithombo ebalulekileyo yokuveliswa kwamandla eselula.
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I-L-Arginine Nitrate CAS: 223253-05-2 uMboneleli woMvelisi
L-Arginine Nitrateluhlobo lwe-amino acid oluyenye yeebhloko zokwakha ezisisiseko zeprotheyini.Yongeza ngokufanelekileyo iprotein synthesis kanye emva kokusebenza kanzima ngokomzimba okanye umsebenzi onzima.Esi sizathu esona sizathu sokuba lo kongeza lukhetho oluphezulu kubadlali kunye nabakhi bomzimba abafuna ukuthatha ukusebenza kwabo kwinqanaba elilandelayo.
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I-Colostrum CAS: 146897-68-9 uMboneleli woMvelisi
Umthubii-glycoprotein, kunye nelungu lentsapho ye-transferrin, ngoko ke ikwezo ziprotheni ezikwazi ukubopha kunye nokudlulisa i-Fe3 + ion (Metz-Boutique et al., 1984) . amathe kunye neenyembezi, kwaye zininzi kakhulu kwi-colostrum yabantu.Iye yabangela umdla kwizazinzulu kangangamashumi eminyaka.
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I-Itraconazole CAS: 84625-61-6 uMboneleli woMvelisi
I-Itraconazole yi-clotrimazole eyenziwe ngokwenziwa, ibe yinto ebanzi yokwenziwa kwe-antifungal agent.I-spectrum yayo ye-antimicrobial kunye ne-antimicrobial mechanism ifana ne-clotrimazole, kodwa inomsebenzi onamandla wokulwa ne-Aspergillus.Isebenzisa impembelelo yayo yokuchasana nokungunda ngokutshintsha i-membrane yeseli yokungunda ikwazi ukungena kunye nomsebenzi we-antibacterial ngokuchasene neentsholongwane zefungal ezingaphezulu kunye nezinzulu.I-spectrum yayo ye-antibacterial ibanzi kwaye inamandla kune-ketoconazole, ikwazi ukuvimbela i-ergosterol synthesis ye-membrane ye-fungal cell, ngaloo ndlela idlala umphumo we-antifungal.
