I-Leflunomide CAS: 75706-12-6 Umthengisi woMvelisi

I-Leflunomide liyeza eliguqula izifo elifumaneka ngomlomo kwaye laqaliswa njenge-Arava e-US ukunyanga isifo samathambo (i-RA); liyeza lokuqala nelokuphela kwalo eliboniswe ukuba linciphisa umonakalo wolwakhiwo lwamalungu e-RA, ngoko ke lijongana nesidingo sezonyango esingafezekiswanga. I-Leflunomide liyeza elixhasa ukucolwa ngokukhawuleza nangokuphantse ngokupheleleyo (isiqingatha sobomi,

Oda okanye Cela iKoteshini

Iinkcukacha zeMveliso

Iithegi zeMveliso

Ukusetyenziswa kunye nesiphumo

I-Leflunomide ayisebenzi, kodwa i-teriflunomide ithintela ukwenziwa kwe-pyrimidine de novo kwiidosi zonyango eziphantsi ngokuthintela i-dihydroorotate dehydrogenase (i-enzyme emisela izinga lokwenziwa kwe-UMP), ukunciphisa ukwenziwa kwe-DNA kunye ne-RNA, kunye nokuthintela umjikelo wokwanda kweeseli kunye nokuveliswa kwee-antibodies. Ukuncipha kwe-dihydroorotate kwi-orotate kwenzeka ngaxeshanye nokunciphisa i-cofactor yayo, i-ubiquinone (i-coenzyme Q). Ukuthintela i-dihydroorotate dehydrogenase yi-teriflunomide kubonisa i-kinetics engenakhuphiswano kwaye engenakhuphiswano. Ukulawulwa kwe-leflunomide kwizigulane ezine-rheumatoid arthritis kubangela ukususwa ngokuthe ngcembe kweeseli ze-B kunye nokunciphisa inkqubo yomzimba yokuzikhusela.

Isampuli yeMveliso

Ukupakisha imveliso:

Iinkcukacha ezongezelelweyo:

Ukwakhiwa	C12H9F3N2O2
Uvavanyo	99%
Inkangeleko	Umgubo omhlophe
Inombolo ye-CAS	75706-12-6
Ukupakisha	25KG
Beka ubomi kwishelufa	iminyaka eyi-2
Indawo yokugcina izinto	Gcina kwindawo epholileyo neyomileyo
Isiqinisekiso	I-ISO.