I-Letrozole CAS: 112809-51-5 Umthengisi woMvelisi

I-Letrozole yinxalenye yesizukulwana esitsha se-aromatase inhibitors ezikhetha kakhulu kwaye sisiphumo se-benzotriazole esenziwe ngokwenziwa. I-Letrozole ithintela i-aromatase ekunciphiseni amanqanaba e-estrogen, ngaloo ndlela ithintela i-estrogen ekukhuthazeni ukukhula kwethumba. Umsebenzi wayo emzimbeni unamandla ngokuphindwe ka-150-250 kunowe-aromatase inhibitors yesizukulwana sokuqala i-Amarante. Njengoko ikhetha kakhulu, ayizukuchaphazela imisebenzi ye-glucocorticoid, i-mineralocorticoid kunye ne-thyroid; nokuba isetyenziswa kakhulu, ayizukuba nemiphumo ethintelayo ekukhutshweni kwe-corticosteroid ye-adrenal, nto leyo eyinika inqanaba eliphezulu lonyango.

Oda okanye Cela iKoteshini

Iinkcukacha zeMveliso

Iithegi zeMveliso

Ukusetyenziswa kunye nesiphumo

I-Letrazole inokwenziwa ngamanyathelo amabini ukusuka kwi-4- bromomethyl-benzonitrile ene-1,2,4-triazole kwaye sisizukulwana sesithathu se-aromatase inhibitor. Sisithinteli esikhethekileyo se-P450arom esithintela ukuguqulwa kwe-androstenedione ibe yi-estrone. Ukuncipha kwe-estrogen ye-plasma kwakhawuleza kwaye kwahlala ixesha elide. Oku kwenziwa ngaphandle kokuthintelwa kwezinye ii-steroid biosynthesis okwenza ukuba ibe sithinteli se-aromatase esikhethiweyo esivavanyiweyo. I-Letrazole inomsebenzi omangalisayo wokulwa nomhlaza, iyanyamezela kwaye ayinazo iziphumo ezinobungozi. Inamandla ngokuphindwe ka-10,000 kune-aminoglutethimide, in vivo, i-aromatase inhibitor yokuqala esekwe kakuhle.

Isampuli yeMveliso

Ukupakisha imveliso:

Iinkcukacha ezongezelelweyo:

Ukwakhiwa	C17H11N5
Uvavanyo	99%
Inkangeleko	Umgubo omhlophe
Inombolo ye-CAS	112809-51-5
Ukupakisha	25KG
Beka ubomi kwishelufa	iminyaka eyi-2
Indawo yokugcina izinto	Gcina kwindawo epholileyo neyomileyo
Isiqinisekiso	I-ISO.