I-Olmesartan CAS: 144689-24-7 uMboneleli woMvelisi

I-Olmesartan medoxomil,phenyl]phenyl]methyl]imidazole-4-carboxylate (i-Benicar, i-Olmetec) isebenzisa inkqubo ye-tetrazolering njengenkqubo yayo ye-acidic, ethatha inxaxheba kwi-inreceptor binding.Xa ilawulwa kwisigulane, ichiza ngokukhawuleza kwaye ngokupheleleyo i-bioactivated yi-ester hydrolysis ye-medoxomil ngexesha lokufunxa kwi-gastrointestinaltract.I-Olmesartan yi-biphenylyltetrazole.Inendima njenge-arhente ye-antihypertensive kunye ne-angiotensin receptor antagonist.

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I-Omesartan ngumchasi osebenzayo kwaye okhethiweyo we-AT2.I-Omesartan axetil inefuthe elinamandla le-antihypertensive.Emva kokulawulwa komlomo, i-de esterified ngokupheleleyo kudonga lwamathumbu amancinci kwaye iguqulelwe kwi-metabolite esebenzayo i-Olmesartan.I-Olmesartan ngumchasi we-angiotensin II we-angiotensin II okhethwe ngokwekhemikhali onqanda ukubophelela kwe-angiotensin II kwi-vascular smooth muscle receptors i-AT1, ngaloo ndlela ivalela isiphumo se-vasoconstrictive se-angiotensin II.

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Iinkcukacha ezongezelelweyo:

Ukuqamba	I-C30H32N6O6
Isivavanyi	99%
Imbonakalo	Umgubo omhlophe
Inombolo yeCAS.	144689-24-7
Ukupakisha	25KG
Beka ubomi kwishelufa	iminyaka eyi-2
Ugcino	Gcina kwindawo epholileyo neyomileyo
Isiqinisekiso	ISO.