I-Olmesartan Medoxomil CAS:144689-63-4 Umthengisi woMvelisi Umfanekiso oPhambili

Umthengisi we-Olmesartan Medoxomil CAS:144689-63-4

I-Olmesartan Medoxomil, sisixhobo esitsha esikhethiweyo nesikhuphisanayo se-angiotensin II type 1 receptor antagonist kwaye sithintela ngamandla iimpendulo ze-Ang.ll-induced pressor. Esi sidakamizwa sithintele ngokukhuphisana ukubopha [125I1]-All kwi-AT1 receptors kwi-bovine adrenal cortical membranes, kodwa asizange sibe nefuthe ekubopheni kwi-AT2 receptors kwi-bovine cerebellar membranes. I-Olmesartan medoxomil ikwabonakalisiwe ukuba inciphisa uxinzelelo lwegazi ngokufanelekileyo kakhulu kune-losartan kunye ne-ACE inhibitor captopril kwaye ngokufanelekileyo njenge-pbloker atenolol.

Oda okanye Cela iKoteshini

Iinkcukacha zeMveliso

Iithegi zeMveliso

Ukusetyenziswa kunye nesiphumo

I-Olmesartan medoxomil sisithinteli se-angiotensin II receptor esisetyenziselwa ukunyanga uxinzelelo lwegazi oluphezulu. I-Olmesartan isebenza ngokuthintela ukubopha kwe-angiotensin II kwii-receptors ze-AT1 kwimisipha yemithambo yegazi. Ngokuthintela ukubopha endaweni yokwenziwa kwe-angiotensin II, i-olmesartan ithintela impendulo engalunganga yokulawula ukukhutshwa kwe-renin. I-Olmesartan medoxomil sisiyobisi esixhasa ukususwa kwe-metabolite esebenzayo, i-olmesartan. I-Olmesartan ineendlela ezimbini zokususa, malunga ne-60% isuswa sisibindi kwaye intsalela isuswa zizintso. Kwiimeko zokusebenza kakubi kwezintso okanye kwisibindi, indlela eyahlukileyo yokukhupha inokubuyisela esonakeleyo.

Isampuli yeMveliso

Ukupakisha imveliso:

Iinkcukacha ezongezelelweyo:

Ukwakhiwa	C29H30N6O6
Uvavanyo	99%
Inkangeleko	Umgubo omhlophe ukuya kowe-beige
Inombolo ye-CAS	144689-63-4
Ukupakisha	25KG
Beka ubomi kwishelufa	iminyaka eyi-2
Indawo yokugcina izinto	Gcina kwindawo epholileyo neyomileyo
Isiqinisekiso	I-ISO.