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I-2,2-DIISOAMYL-1,3-PROPANEDIOL CAS:403519-64-2
I-2,2-Diisoamyl-1,3-propanediol yikhompawundi yendalo ebonakaliswa ngumqolo wayo we-propanediol kunye namaqela amabini e-isoamyl anamathele kwikhabhoni yesibini. Lulwelo olungenambala, oluxineneyo olwaziwa ngeempawu zalo ezifana ne-glyceryl. Le khompawundi ifumene ingqalelo kwiinkalo ezahlukeneyo ngenxa yesakhiwo sayo esikhethekileyo seemolekyuli kunye nokusetyenziswa okunokwenzeka kwisayensi yezinto kunye neekhemikhali.
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I-METHYL OXALYL CHLORIDE CAS:5781-53-3
I-Methyl oxalyl chloride yikhompawundi ephambili enuka kamnandi ebonakaliswa bubukho bamaqela amabini e-carbonyl kunye ne-atom ye-chlorine enamathele kwiqela le-methyl. Ngefomyula yekhemikhali i-C4H3ClO3, le khompawundi isebenza njengendawo ebalulekileyo ekuhlanganisweni kwezinto eziphilayo, ngakumbi ekulungiseleleni amayeza ahlukeneyo kunye neekhemikhali zezolimo. Ukusebenza kwayo kuvela kubukho bemisebenzi ye-oxalyl kunye ne-chlorinated, evumela ukuba ithathe inxaxheba kwiinguqu ezahlukeneyo zeekhemikhali. Uphando kwi-methyl oxalyl chloride lubonise ukubaluleka kwayo ekuhlanganiseni iimolekyuli ezintsonkothileyo, kubandakanya ii-heterocycles ezixabisekileyo kunye nezinye iikhompawundi ze-bioactive.
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I-Ethyl oxalyl monochloride CAS:4755-77-5
I-ethyl oxalyl monochloride yikhompawundi ebalulekileyo yendalo ebonakaliswa liqela le-ethyl elinamathele kwi-oxalyl moiety, eliquka amaqela amabini e-carbonyl kunye ne-atom enye ye-chlorine. Ngefomula yemolekyuli i-C5H7ClO3, le khompawundi yaziwa ngokubanzi njengeyona nto ibalulekileyo kwi-organic synthesis, ngakumbi kumashishini amayeza kunye neekhemikhali zezolimo. Ukusebenza kwayo okwahlukileyo kuvela kwimisebenzi yayo ye-oxalyl kunye ne-chlorinated, evumela ukuba ibandakanyeke kwiinguqu ezahlukeneyo zeekhemikhali. Abaphandi bahlolisise i-ethyl oxalyl monochloride ukuze bafumane ukusetyenziswa kwayo ekudaleni iimolekyuli ezintsonkothileyo ezinemisebenzi eyahlukeneyo yebhayoloji.
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I-DL-4-Chlorophenylglycine CAS: 6212-33-5
I-DL-4-Chlorophenylglycine yikhemikhali efumene umdla omkhulu kwicandelo lekhemistri yamayeza kunye ne-pharmacology. Njenge-glycine derivative, ineqela le-chlorophenyl, eliphucula iipropati zayo zokubopha kunye nomsebenzi webhayoloji. Le khompawundi iye yafundwa ngenxa yezicelo zayo ezinokubakho ekunyangeni iingxaki ezahlukeneyo ze-neurological, ngakumbi ngokuguqula ii-glutamate receptors. Ulwakhiwo olulodwa lwe-DL-4-Chlorophenylglycine lukwavumela ukuba isebenze njengomchasi okanye i-agonist ngokuxhomekeke kwindawo ekuyo, nto leyo eyenza ukuba ibe ngumviwa oguquguqukayo wophando malunga nonyango lwe-neuropharmacological. Ukwenziwa kwayo kunye nokuchazwa kwayo kuyaqhubeka nokuba ziindawo zophando olusebenzayo.
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I-DRONEDARONE HYDROCHLORIDE CAS: 141625-93-6
I-Dronedarone hydrochloride liyeza elilwa nokubetha kwentliziyo elisetyenziselwa kakhulu ukulawula i-atrial fibrillation kunye ne-atrial flutter. Eli chiza livela kwi-amiodarone, lenzelwe ukubonelela ngezibonelelo ezifanayo zonyango ngelixa linciphisa ezinye zeziphumo ezimbi ezinxulumene ne-amiodarone, ngakumbi ubuthi bayo be-thyroid kunye ne-pulmonary. I-Dronedarone isebenza ngokwandisa amandla okusebenza kunye nexesha lokuchasana nezicubu zentliziyo, izinzisa isigqi sentliziyo, kwaye inciphise umngcipheko wokulaliswa esibhedlele ngenxa yeziganeko zentliziyo. Ivunyiwe ukuba isetyenziswe kwezonyango kumazwe ahlukeneyo, i-dronedarone imele inkqubela phambili ebalulekileyo kulawulo lwe-pharmacological lwe-atrial arrhythmias.
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i-valproic acid CAS:99-66-1
I-Valproic acid, ekwaziwa ngokuba yi-2-propylpentanoic acid, liyeza elisetyenziswa kakhulu lokulwa nokuxhuzula kunye nokuzinzisa imood elimiselwe kakhulu ukunyanga isifo sokuwa kunye nesifo se-bipolar. Yafunyanwa ngeminyaka yoo-1960, isebenza ngokunyusa amanqanaba e-gamma-aminobutyric acid (GABA) engqondweni, i-neurotransmitter ebalulekileyo enceda ukulawula ukuvuseleleka kwe-neuronal. I-Valproic acid ifumene udumo kungekuphela nje ngokusebenza kwayo ekulawuleni ukuxhuzula kodwa nakwindima yayo ekuthinteleni iintloko ezibuhlungu kunye nokunyanga iimeko ezithile zengqondo. Iprofayili yayo entle yezonyango iyenza ibe sisixhobo esibalulekileyo sonyango kwi-neurology nakwi-psychiatry.
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I-Sodium Valproate CAS:1069-66-5
I-Sodium valproate, ityuwa yesodium ye-valproic acid, liyeza elilwa nokuxhuzula kunye nokuqinisa imood elisetyenziswa kakhulu kunyango lwesifo sokuwa kunye nesifo se-bipolar. Isebenza ngokunyusa amanqanaba e-gamma-aminobutyric acid (GABA) engqondweni, i-neurotransmitter edlala indima ebalulekileyo ekunciphiseni ukuvuseleleka kwe-neuronal. Yamkelwe ngasekupheleni kwenkulungwane yama-20, i-sodium valproate yaziwa ngokusebenza kwayo kwiintlobo ezahlukeneyo zokuxhuzula kwaye ikwasetyenziswa ekuthinteleni i-migraine. Iprofayili yayo entle yezonyango yenze ukuba ibe lukhetho olubalulekileyo lonyango kwi-neurology nakwi-psychiatry.
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I-ETHYL 5-AMINOBENZOFURAN-2-CARBOXYLATE CAS:174775-48-5
I-Ethyl 5-aminobenzofuran-2-carboxylate yikhemikhali ekwiklasi yee-benzofuran derivatives, ezibalulekileyo kwikhemistri yezonyango ngenxa yemisebenzi yazo eyahlukeneyo yebhayoloji. Le khemikhali ineqela elisebenzayo le-ethyl ester kunye nokutshintshwa kwe-amino kwiringi ye-benzofuran, okwenza ukuba ibe sisakhiwo esiguquguqukayo sokwenza iimolekyuli ezisebenzayo. I-Ethyl 5-aminobenzofuran-2-carboxylate ifumene ingqalelo kuphando lwamayeza ngenxa yezicelo zayo ezinokubakho ekuphuhliseni iiarhente zonyango ezintsha, ngakumbi kwiindawo ezifana nonyango oluchasene nokuvuvukala, oluthintela iintlungu, okanye olulwa neentsholongwane, ngenxa yeempawu ezizodwa zesakhiwo ezinikezelwa yi-benzofuran scaffold.
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I-Diethyl benzylmalonate CAS:607-81-8
I-Diethyl benzylmalonate yikhompawundi ebalulekileyo yendalo esetyenziswa kakhulu kwikhemistri yokwenziwa, ngakumbi ekulungiseleleni amayeza ahlukeneyo kunye neekhemikhali zezolimo. Le mveliso ye-malonic acid ineeqela ezimbini ze-ethyl ester kunye ne-benzyl substituent, eyonyusa ukwenzeka kwayo kwi-reactions yokutshintshwa kwe-nucleophilic. I-Diethyl benzylmalonate isebenza njengebhloko yokwakha eguquguqukayo ekuhlanganiseni iimolekyuli ezisebenzayo kwibhayoloji, kubandakanya izinto eziphambili ekuphuhlisweni kwamayeza. Ulwakhiwo lwayo olwahlukileyo kunye neempawu zokusebenza zenza ukuba ibe yikhompawundi ebalulekileyo kwikhemistri yamayeza, ivumela iikhemistri ukuba ziphonononge iindlela ezahlukeneyo zokwenziwa zokuphuhlisa unyango olutsha.
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I-Indazole CAS:271-44-3
I-Indazole yi-compound enuka kamnandi ejikeleza kabini equlathe i-pyrazole enamalungu amahlanu edityaniswe kwi-benzene enamalungu amathandathu. Olu lwakhiwo lwe-heterocyclic luyaziwa ngemisebenzi yalo eyahlukeneyo yebhayoloji kunye nokusetyenziswa okunokwenzeka kwikhemistri yezonyango. I-Indazole kunye nezinto eziphuma kuyo zifumene ingqalelo enkulu ngenxa yokubandakanyeka kwazo kwiimpawu ezahlukeneyo ze-pharmacological, ezifana ne-anti-inflammatory, anti-cancer, kunye ne-antimicrobial effects. Le compound isebenza njengesiseko esibalulekileyo kuphuhliso lwamayeza, ngakumbi kuyilo lwezonyango ezintsha ezijolise kwizifo ezininzi. Uphando oluqhubekayo luyaqhubeka nokuphonononga iindlela zokwenziwa kunye nemiphumo yebhayoloji enxulumene ne-indazole.
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I-ETHYL 5-NITROBENZOURAN-2-CARBOXYLATE CAS:69604-00-8
I-Ethyl 5-nitrobenzofuran-2-carboxylate yinxalenye ebalulekileyo kwicandelo le-organic chemistry, ngakumbi ngaphakathi kolawulo lwee-heterocyclic compounds. Njenge-nitro-substituted benzofuran derivative, ibonisa iipropati zeekhemikhali ezikhethekileyo kunye nemisebenzi yebhayoloji eyenza ukuba ibe yindawo ekhangayo yophando lwezonyango. Ubukho beqela le-nitro buphucula ukusebenza kwayo, okuvumela ukusetyenziswa okunokwenzeka ekuqulunqweni kwamayeza amatsha. I-Ethyl 5-nitrobenzofuran-2-carboxylate ifumene ingqalelo ngokusetyenziswa kwayo okunokwenzeka ekuphuhliseni ii-anti-inflammatory, antimicrobial, kunye ne-anticancer agents, igxininisa ukubaluleka kwayo ekuphuculeni i-medicine yezonyango kunye namaqhinga okufumanisa amayeza.
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I-4-Bromophenylacetone CAS: 6186-22-7
I-4-Bromophenylacetone yi-aromatic ketone ebonakaliswa yinto ethatha indawo ye-bromine kwiringi ye-phenyl, kunye neqela elisebenzayo le-acetone. Le khompawundi ifumene ingqalelo kwi-organic synthesis ngenxa yokuguquguquka kwayo njengesiseko sokwakha kwiimolekyuli ezintsonkothileyo, kubandakanya amayeza kunye neekhemikhali zezolimo. Ubukho be-athomu ye-bromine buphucula uphawu lwayo lwe-electrophilic, buququzelela iimpendulo ezahlukeneyo kwiindlela zokwenziwa. Ukongeza, i-4-bromophenylacetone ibonakalise imisebenzi enokubakho yebhayoloji, okwenza ukuba ibe yinto enomdla kwikhemistri yamayeza ukuze kuhlolwe ngakumbi kwaye kusetyenziswe ekufumaneni amayeza.
