Umthengisi weRosuvastatin Calcium CAS:147098-20-2

I-Rosuvastatin calcium sisithinteli esikhethiweyo se-HMG-CoA reductase. I-HMG-CoA reductase inhibitor yi-enzyme ethintela izinga le-transition hydroxy-3-methylglutaryl coenzyme A ukuya kwi-valerate A (I-precursor ye-cholesterol). Indawo ephambili yokusebenza kwe-rosuvastatin sisibindi-amalungu ekujoliswe kuwo okunciphisa i-cholesterol. I-Rosuvastatin yonyusa inani lee-receptors ze-hepatic LDL kumphezulu weseli, ikhuthaza ukufunxwa kunye ne-catabolism ye-LDL, ithintela ukwenziwa kwe-VLDL kwisibindi, ngaloo ndlela inciphisa inani lilonke lee-VLDL kunye nee-LDL particles. I-Rosuvastatin calcium inako ukuthintela ngokukhuphisana i-liver methylglutaryl coenzyme A reductase, kwaye iphinda isebenzise impembelelo yayo entle ekunciphiseni amafutha. Inesiqingatha sobomi obude. Isini kunye nobudala bezigulane azinampembelelo ibalulekileyo kwi-metabolism yamayeza.