I-S-Nitrosoglutathione CAS: 57564-91-7 Ixabiso lomenzi

I-rosoglutathione (GSNO) idlala indima ebalulekileyo ekudluliseleni imiyalezo kwiseli kwaye ineziphumo ezahlukeneyo kunye nokusetyenziswa. Nazi ezinye iingongoma eziphambili:

Ulawulo lweNitric Oxide (NO): I-GSNO isebenza njengendawo yokugcina i-NO, iyikhupha ngendlela elawulwayo. I-NO yimolekyuli yokubonisa eneziphumo ezahlukeneyo emzimbeni, kubandakanya ukusasazeka kwemithambo-luvo, ukudluliselwa kwemithambo-luvo, kunye nokulawulwa kwempendulo yomzimba.

Impilo yeNtliziyo neMithambo: I-GSNO inceda ekulawuleni ithoni yemithambo yegazi kunye noxinzelelo lwegazi ngokukhuthaza ukusasazeka kwemithambo yegazi kunye nokuthintela ukuhlangana kweeplatelet. Ikwakhusela kuxinzelelo lwe-oxidative kunye nokudumba kwinkqubo yentliziyo.

Iziphumo Zokulwa Nokudumba: I-GSNO ineempawu zokulwa nokudumba ngokuthintela ukuveliswa kweempawu zokudumba ezifana nee-cytokines kunye neemolekyuli zokunamathela. Inokunceda ekunciphiseni ukudumba kwizifo ezahlukeneyo, kubandakanya i-asthma, i-arthritis, kunye nesifo sokudumba kwamathumbu.

Ukukhusela imithambo-luvo: I-GSNO ibonakalisiwe ukuba inefuthe lokukhusela imithambo-luvo ngokunciphisa uxinzelelo lwe-oxidative kunye nokudumba kwemithambo-luvo. Isenokuba nefuthe elinokwenzeka kwizifo zemithambo-luvo ezifana ne-Alzheimer's kunye ne-Parkinson's.

Iimpawu Zokulwa Nomhlaza: I-GSNO ifundwe ngenxa yamandla ayo okulwa nomhlaza. Inokubangela i-apoptosis (ukufa kweeseli okucwangcisiweyo) kwiiseli zomhlaza, ithintele ukukhula kwethumba kunye nokwanda kwe-metastasis, kwaye iphucule ukusebenza kakuhle kwamayeza e-chemotherapy.

Ukuphiliswa Kwenxeba: I-GSNO iphandwe ngendima yayo ekuphilisweni kwenxeba ngenxa yokukwazi kwayo ukukhuthaza ukuvuselelwa kwezicubu, i-angiogenesis (ukwakheka kwemithambo yegazi emitsha), kunye nokuhlanganiswa kwe-collagen.

Umsebenzi we-Antioxidant: I-GSNO isebenza njenge-antioxidant ngokukhupha iintlobo ze-oxygen eziyingozi (i-ROS) kunye nokukhusela iiseli kumonakalo we-oxidative.