I-Sirolimus CAS:53123-88-9

Uxinzelelo lwe-Immunosuppression: I-Sirolimus isetyenziselwa ukuthintela ukwaliwa kwamalungu omzimba emva kokufakelwa izintso. Idla ngokumiselwa kunye nezinye izinto ezithintela i-immunosuppression ukunciphisa umngcipheko wokwaliwa kunye nokuphucula ukusinda kwe-graft. Ugqubuthelo lwe-Coronary Stent: Kwi-cardiology, i-sirolimus isetyenziswa kwi-stents ezithintela amayeza ukuthintela i-restenosis (ukuncipha kwakhona) kwemithambo yegazi emva kwe-angioplasty, inceda ekugcineni i-patency yemithambo yegazi kunye nokunciphisa isidingo sokungenelela okuphindaphindiweyo. Unyango lwe-Lymphangioleiomyomatosis (LAM): I-Sirolimus ivunyiwe kunyango lwe-LAM, isifo semiphunga esingaqhelekanga, ukuphucula ukusebenza kwemiphunga kunye nokuqhubela phambili kwesifo kancinci. Unyango lomhlaza: Isetyenziswa kunyango lweentlobo ezithile zomhlaza, kubandakanya i-renal cell carcinoma kunye nabasetyhini abasemva kokuya exesheni abanomhlaza webele oqhubele phambili, obonisa iziphumo zokulwa nokwanda kwamalungu omzimba. Iimeko zesikhumba: I-Sirolimus iphandwe ngamandla ayo ekunyangeni iimeko ezahlukeneyo zesikhumba ezifana ne-psoriasis, i-atopic dermatitis, kunye ne-angiofibromas ezinxulumene ne-tuberous sclerosis complex. Ii-Vascular Grafts: Kutyando lwemithambo yegazi, ii-grafts ezigqunywe yi-sirolimus zisetyenziselwa ukuthintela i-intimal hyperplasia kunye nokukhuthaza i-patency engcono yexesha elide ekuvuseleleni imithambo yegazi. Unyango loPhando: Uphando luyaqhubeka malunga nokusetyenziswa kwe-sirolimus kwizifo zokuzikhusela komzimba, ezifana ne-systemic lupus erythematosus, nakwicandelo lonyango lokuvuselela kunye nobunjineli bezicubu. Ngamafutshane, i-sirolimus idlala indima ebalulekileyo kunyango lokufakelwa, i-cardiology, i-oncology, kunye neendawo ezahlukeneyo zonyango ngenxa yeempawu zayo zokunciphisa amasosha omzimba kunye nokuthintela ukwanda, okufaka isandla kwiziphumo eziphuculweyo zesigulana kunye nokuqhubela phambili unyango lwezonyango.