Umthengisi weSodium Alpha-Ketoisocaproate CAS:4502-00-5

I-Sodium Alpha-Ketoisocaproate yi-leucine metabolite eyaziwa ngokubangela ukukhutshwa kwe-insulin kwiiseli ze-β zepancreas. Ukufakwa kwe-aα-Ketoisocaproate ngaphakathi kufunyenwe kuphucula imeko ye-endotoxemia. Imizimba ye-ketone efunyenweyo efunyenwe ekuguqulweni kwayo, inokusebenza njengomthombo wamandla. Ukuqokelelwa kwe-α-Ketoisocaproic acid kubonakala kwi-branched chain ketoaciduria, ebangelwa kukungabikho komsebenzi we-branched chain L-2-keto acid dehydrogenase. I-α-Ketoisocaproic acid ibangela ukwahlukana kwi-oxidative phosphorylation reaction kwaye isebenza njengesithinteli se-metabolic ye-α-ketoglutarate dehydrogenase. Ke ngoko, kukhokelela kwisiphene kwi-mitochondrial homeostasis, ebonwa kwi-branched chain ketoaciduria.